Avidity Partners Management LP

CIK

1791827

Location

DALLAS, TX

Portfolio Value

Micro $4,015,800

Diversification

Diversified

Filing Date

Global Rank

#3,052 / 8,420 ▼ 256

Top Industry

Biotechnology 65.4%

3Y Alpha vs SPY

-0.1%

Period ended 6 months ago

Filed Feb 17, 2026 · 4mo

24 quarters · since Mar 2020

Clone Performance

Jun 2023–Jun 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+73.6%

SPY

+74.2%

Annualised alpha

-0.1%

Max drawdown

−37.9%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

39 positions · as of Dec 31, 2025 · Δ vs Sep 30, 2025

Top Position

25.0%

−4.3 pts

Top 5

58.4%

+3.2 pts

Top 10

71.9%

+4.0 pts

HHI

1,095

Diversified−105

Portfolio Trend

24 quarters · across all stocks

Sector Breakdown

As of Dec 31, 2025

Sector	% Portfolio	Value	Positions
Healthcare	98.8%	$342,677,779	38
Consumer Defensive	1.2%	$4,015,800	1

Last Quarter's Activity

Export CSV

Dec 31, 2025 vs Sep 30, 2025

Added To

Positions the filer increased

5 positions

Ticker	Company	Δ Shares	Shares	Value
JBIO	Jade Biosciences, Inc.	+273,522	1,400,708	$21,612,924
CATX	Perspective Therapeutics, Inc.	+216,700	3,210,733	$8,829,515
RGEN	Repligen Corp	+27,000	50,300	$8,242,158
INSM	INSMED Inc	+6,100	17,700	$3,080,508
MCK	Mckesson Corp	+3,720	9,520	$7,809,160
No positions match the current search.

Trimmed

Positions the filer reduced

19 positions

Ticker	Company	Δ Shares	Shares	Value
CNTX	Context Therapeutics Inc.	−3,477,000	5,504,855	$8,092,136
SCYX	Scynexis Inc	−1,268,868	2,081,660	$1,315,609
DNTH	Dianthus Therapeutics, Inc. /DE/	−1,100,000	2,104,184	$86,713,422
PFE	Pfizer Inc	−162,800	203,600	$5,069,640
GMAB	Genmab A/S	−156,100	92,000	$2,833,600
CGON	CG Oncology, Inc.	−128,200	1,472,699	$61,146,462
PHAT	Phathom Pharmaceuticals, Inc.	−99,924	206,076	$3,418,800
TEVA	Teva Pharmaceutical Industries Ltd	−92,700	417,300	$13,023,933
MDT	Medtronic plc	−83,000	107,600	$10,336,056
NTRA	Natera, Inc.	−58,600	11,800	$2,703,262
BSX	Boston Scientific Corp	−49,800	114,500	$10,917,575
DHR	Danaher Corp /De/	−37,700	17,000	$3,891,640
ACAD	Acadia Pharmaceuticals Inc	−37,100	106,900	$2,855,299
KVUE	Kenvue Inc.	−32,400	232,800	$4,015,800
TMO	Thermo Fisher Scientific Inc.	−12,200	6,700	$3,882,315
EHC	Encompass Health Corp	−10,300	31,600	$3,354,024
COR	Cencora, Inc.	−9,600	9,400	$3,174,850
HQY	Healthequity, Inc.	−8,400	16,900	$1,548,209
CI	Cigna Group	−5,000	11,600	$3,192,668
No positions match the current search.

New Positions

Positions the filer opened this quarter

11 positions

Ticker	Company	Shares	Value
ALNY	Alnylam Pharmaceuticals, Inc.	21,000	$8,350,650
ICLR	Icon PLC	33,100	$6,031,482
A	Agilent Technologies, Inc.	41,500	$5,646,905
CNC	Centene Corp	119,400	$4,913,310
NVO	Novo Nordisk A S	67,300	$3,424,224
WAT	Waters Corp /De/	8,100	$3,076,623
ACHC	Acadia Healthcare Company, Inc.	169,000	$2,398,110
ITGR	Integer Holdings Corp	29,800	$2,337,214
PVLA	Palvella Therapeutics, Inc.	19,300	$2,020,131
IQV	Iqvia Holdings Inc.	4,400	$991,804
CORT	Corcept Therapeutics Inc	22,000	$765,600
No positions match the current search.

Sold Out

Positions the filer fully exited

13 positions

Ticker	Company	Shares	Value
BMY	Bristol Myers Squibb Co	257,600	$11,617,760
UNH	Unitedhealth Group Inc	17,800	$6,146,340
ARVN	Arvinas, Inc.	698,363	$5,950,052
JNJ	Johnson & Johnson	26,800	$4,969,256
ABBV	AbbVie Inc.	19,800	$4,584,492
CARL	Carlsmed, Inc.	321,912	$4,310,401
ARQT	Arcutis Biotherapeutics, Inc.	214,400	$4,041,440
EXAS	EXACT SCIENCES CORP	73,600	$4,026,656
ASND	Ascendis Pharma A/S	14,500	$2,882,745
BEAM	Beam Therapeutics Inc.	112,000	$2,718,240
WVE	Wave Life Sciences Ltd.	297,500	$2,177,700
XENE	Xenon Pharmaceuticals Inc.	53,400	$2,144,010
IMRX	Immuneering Corp	90,900	$636,300
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

1 positions · $4,015,800 total · Consumer Defensive only · as of Dec 31, 2025

All sectors Consumer Defensive Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio	History
KVUE	Kenvue Inc. Consumer Defensive	Reduced	232,800	-32,400	$4,015,800	−6.7%	100.00%