Avidity Partners Management LP
CIK
1791827
Location
DALLAS, TX
Portfolio Value
Small
$504,281,336
Diversification
Moderately concentrated
Filing Date
Global Rank
#2,598
/ 8,622
▲ 673
· as of Mar 2026
Top Industry
Biotechnology
80.6%
3Y Alpha vs SPY
+1.6%
Period ended 4 months ago
Filed May 28, 2026 · 2mo
25 quarters · since Mar 2020
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+95.0%
SPY
+67.9%
Annualised alpha
+6.1%
Max drawdown
−38.5%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 99% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
52 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
35.0%
+10.0 pts
Top 5
68.6%
+10.2 pts
Top 10
80.6%
+8.7 pts
HHI
1,668
Moderately concentrated+573
Portfolio Trend
25 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 99.3% | $500,762,736 |
| Consumer Defensive | 0.5% | $2,660,600 |
| Consumer Cyclical | 0.2% | $858,000 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
11 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CATX | Perspective Therapeutics, Inc. | +2,839,266 | 6,049,999 | $25,228,495 | |
| IMUX | Immunic, Inc. | +2,000,000 | 6,699,411 | $7,436,346 | |
| KPTI | Karyopharm Therapeutics Inc. | +329,175 | 463,741 | $2,583,037 | |
| ELVN | Enliven Therapeutics, Inc. | +259,700 | 400,000 | $15,680,000 | |
| ORKA | Oruka Therapeutics, Inc. | +100,000 | 760,424 | $37,298,797 | |
| PVLA | Palvella Therapeutics, Inc. | +50,700 | 70,000 | $8,725,500 | |
| PHAT | Phathom Pharmaceuticals, Inc. | +43,314 | 249,390 | $2,770,722 | |
| TEVA | Teva Pharmaceutical Industries Ltd | +32,800 | 450,100 | $13,557,012 | |
| RGEN | Repligen Corp | +27,500 | 77,800 | $9,166,396 | |
| EHC | Encompass Health Corp | +10,400 | 42,000 | $4,062,660 | |
| CORT | Corcept Therapeutics Inc | +8,000 | 30,000 | $1,209,300 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CNTX | Context Therapeutics Inc. | −506,588 | 4,998,267 | $13,095,459 | |
| CGON | CG Oncology, Inc. | −183,751 | 1,288,948 | $87,236,000 | |
| KVUE | Kenvue Inc. | −132,800 | 100,000 | $1,724,000 | |
| ACAD | Acadia Pharmaceuticals Inc | −93,933 | 12,967 | $288,645 | |
| BSX | Boston Scientific Corp | −54,500 | 60,000 | $3,765,000 | |
| CNC | Centene Corp | −49,400 | 70,000 | $2,291,800 | |
| GMAB | Genmab A/S | −42,000 | 50,000 | $1,341,500 | |
| ICLR | Icon PLC | −17,100 | 16,000 | $1,770,560 | |
| MDT | Medtronic plc | −7,600 | 100,000 | $8,665,000 | |
| NTRA | Natera, Inc. | −2,800 | 9,000 | $1,799,910 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| VIR | Vir Biotechnology, Inc. | 950,000 | $8,512,000 | |
| AKTS | Aktis Oncology, Inc. | 468,566 | $8,382,645 | |
| DXCM | Dexcom Inc | 90,000 | $5,652,000 | |
| HUM | Humana Inc | 25,000 | $4,334,750 | |
| TENX | Tenax Therapeutics, Inc. | 215,934 | $3,452,784 | |
| GILD | Gilead Sciences, Inc. | 20,000 | $2,787,400 | |
| MSLE | Satellos Bioscience Inc. | 387,769 | $2,183,139 | |
| PODD | Insulet Corp | 10,000 | $2,098,400 | |
| CRL | Charles River Laboratories International, Inc. | 10,000 | $1,725,000 | |
| CRVS | Corvus Pharmaceuticals, Inc. | 115,000 | $1,682,450 | |
| HIMS | Hims & Hers Health, Inc. | 75,000 | $1,557,000 | |
| RVMD | Revolution Medicines, Inc. | 15,000 | $1,458,750 | |
| GPCR | Structure Therapeutics Inc. | 30,000 | $1,446,000 | |
| TEM | Tempus AI, Inc. | 25,000 | $1,130,500 | |
| ABVX | Abivax S.A. | 10,000 | $1,113,500 | |
| UNH | Unitedhealth Group Inc | 3,800 | $1,028,242 | |
| ABT | Abbott Laboratories | 10,000 | $1,026,700 | |
| NTLA | Intellia Therapeutics, Inc. | 75,000 | $961,500 | |
| ODD | Oddity Tech Ltd | 70,000 | $936,600 | |
| MLTX | MoonLake Immunotherapeutics | 50,000 | $932,000 | |
| PTON | Peloton Interactive, Inc. | 200,000 | $858,000 | |
| AVR | Anteris Technologies Global Corp. | 150,000 | $832,500 | |
| BBIO | BridgeBio Pharma, Inc. | 10,000 | $742,600 | |
| ABUS | Arbutus Biopharma Corp | 125,000 | $562,500 | |
| BBOT | BridgeBio Oncology Therapeutics, Inc. | 43,853 | $392,484 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
15 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ALNY | Alnylam Pharmaceuticals, Inc. | 21,000 | $8,350,650 | |
| MCK | Mckesson Corp | 9,520 | $7,809,160 | |
| A | Agilent Technologies, Inc. | 41,500 | $5,646,905 | |
| PFE | Pfizer Inc | 203,600 | $5,069,640 | |
| DHR | Danaher Corp /De/ | 17,000 | $3,891,640 | |
| TMO | Thermo Fisher Scientific Inc. | 6,700 | $3,882,315 | |
| NVO | Novo Nordisk A S | 67,300 | $3,424,224 | |
| CI | Cigna Group | 11,600 | $3,192,668 | |
| COR | Cencora, Inc. | 9,400 | $3,174,850 | |
| INSM | INSMED Inc | 17,700 | $3,080,508 | |
| WAT | Waters Corp /De/ | 8,100 | $3,076,623 | |
| ACHC | Acadia Healthcare Company, Inc. | 169,000 | $2,398,110 | |
| ITGR | Integer Holdings Corp | 29,800 | $2,337,214 | |
| HQY | Healthequity, Inc. | 16,900 | $1,548,209 | |
| IQV | Iqvia Holdings Inc. | 4,400 | $991,804 | |
| No positions match the current search. | ||||
52 tracked positions ·
$504,281,336 total
· as of Mar 31, 2026
Showing 1–50
of 52 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| DNTH |
Dianthus Therapeutics, Inc. /DE/
Healthcare
|
Held | 2,104,184 | $176,583,121 | 35.02% | |
| CGON |
CG Oncology, Inc.
Healthcare
|
Reduced | 1,288,948 | $87,236,000 | 17.30% | |
| ORKA |
Oruka Therapeutics, Inc.
Healthcare
|
Added | 760,424 | $37,298,797 | 7.40% | |
| CATX |
Perspective Therapeutics, Inc.
Healthcare
|
Added | 6,049,999 | $25,228,495 | 5.00% | |
| JBIO |
Jade Biosciences, Inc.
Healthcare
|
Held | 1,400,708 | $19,679,947 | 3.90% | |
| ELVN |
Enliven Therapeutics, Inc.
Healthcare
|
Added | 400,000 | $15,680,000 | 3.11% | |
| TEVA |
Teva Pharmaceutical Industries Ltd
Healthcare
|
Added | 450,100 | $13,557,012 | 2.69% | |
| CNTX |
Context Therapeutics Inc.
Healthcare
|
Reduced | 4,998,267 | $13,095,459 | 2.60% | |
| RGEN |
Repligen Corp
Healthcare
|
Added | 77,800 | $9,166,396 | 1.82% | |
| PVLA |
Palvella Therapeutics, Inc.
Healthcare
|
Added | 70,000 | $8,725,500 | 1.73% | |
| MDT |
Medtronic plc
Healthcare
|
Reduced | 100,000 | $8,665,000 | 1.72% | |
| VIR |
Vir Biotechnology, Inc.
Healthcare
|
NEW | 950,000 | $8,512,000 | 1.69% | |
| AKTS |
Aktis Oncology, Inc.
Healthcare
|
NEW | 468,566 | $8,382,645 | 1.66% | |
| IMUX |
Immunic, Inc.
Healthcare
|
Added | 6,699,411 | $7,436,346 | 1.47% | |
| DXCM |
Dexcom Inc
Healthcare
|
NEW | 90,000 | $5,652,000 | 1.12% | |
| HUM |
Humana Inc
Healthcare
|
NEW | 25,000 | $4,334,750 | 0.86% | |
| EHC |
Encompass Health Corp
Healthcare
|
Added | 42,000 | $4,062,660 | 0.81% | |
| BSX |
Boston Scientific Corp
Healthcare
|
Reduced | 60,000 | $3,765,000 | 0.75% | |
| TENX |
Tenax Therapeutics, Inc.
Healthcare
|
NEW | 215,934 | $3,452,784 | 0.68% | |
| GILD |
Gilead Sciences, Inc.
Healthcare
|
NEW | 20,000 | $2,787,400 | 0.55% | |
| PHAT |
Phathom Pharmaceuticals, Inc.
Healthcare
|
Added | 249,390 | $2,770,722 | 0.55% | |
| KPTI |
Karyopharm Therapeutics Inc.
Healthcare
|
Added | 463,741 | $2,583,037 | 0.51% | |
| CNC |
Centene Corp
Healthcare
|
Reduced | 70,000 | $2,291,800 | 0.45% | |
| MSLE |
Satellos Bioscience Inc.
Healthcare
|
NEW | 387,769 | $2,183,139 | 0.43% | |
| PODD |
Insulet Corp
Healthcare
|
NEW | 10,000 | $2,098,400 | 0.42% | |
| SCYX |
Scynexis Inc
Healthcare
|
Reduced | 2,081,660 | $1,908,882 | 0.38% | |
| NTRA |
Natera, Inc.
Healthcare
|
Reduced | 9,000 | $1,799,910 | 0.36% | |
| ICLR |
Icon PLC
Healthcare
|
Reduced | 16,000 | $1,770,560 | 0.35% | |
| CRL |
Charles River Laboratories International, Inc.
Healthcare
|
NEW | 10,000 | $1,725,000 | 0.34% | |
| KVUE |
Kenvue Inc.
Consumer Defensive
|
Reduced | 100,000 | $1,724,000 | 0.34% | |
| CRVS |
Corvus Pharmaceuticals, Inc.
Healthcare
|
NEW | 115,000 | $1,682,450 | 0.33% | |
| HIMS |
Hims & Hers Health, Inc.
Healthcare
|
NEW | 75,000 | $1,557,000 | 0.31% | |
| RVMD |
Revolution Medicines, Inc.
Healthcare
|
NEW | 15,000 | $1,458,750 | 0.29% | |
| GPCR |
Structure Therapeutics Inc.
Healthcare
|
NEW | 30,000 | $1,446,000 | 0.29% | |
| GMAB |
Genmab A/S
Healthcare
|
Reduced | 50,000 | $1,341,500 | 0.27% | |
| CORT |
Corcept Therapeutics Inc
Healthcare
|
Added | 30,000 | $1,209,300 | 0.24% | |
| TEM |
Tempus AI, Inc.
Healthcare
|
NEW | 25,000 | $1,130,500 | 0.22% | |
| ABVX |
Abivax S.A.
Healthcare
|
NEW | 10,000 | $1,113,500 | 0.22% | |
| UNH |
Unitedhealth Group Inc
Healthcare
|
NEW | 3,800 | $1,028,242 | 0.20% | |
| ABT |
Abbott Laboratories
Healthcare
|
NEW | 10,000 | $1,026,700 | 0.20% | |
| NTLA |
Intellia Therapeutics, Inc.
Healthcare
|
NEW | 75,000 | $961,500 | 0.19% | |
| ODD |
Oddity Tech Ltd
Consumer Defensive
|
NEW | 70,000 | $936,600 | 0.19% | |
| MLTX |
MoonLake Immunotherapeutics
Healthcare
|
NEW | 50,000 | $932,000 | 0.18% | |
| PTON |
Peloton Interactive, Inc.
Consumer Cyclical
|
NEW | 200,000 | $858,000 | 0.17% | |
| AVR |
Anteris Technologies Global Corp.
Healthcare
|
NEW | 150,000 | $832,500 | 0.17% | |
| BBIO |
BridgeBio Pharma, Inc.
Healthcare
|
NEW | 10,000 | $742,600 | 0.15% | |
| ABUS |
Arbutus Biopharma Corp
Healthcare
|
NEW | 125,000 | $562,500 | 0.11% | |
| BBOT |
BridgeBio Oncology Therapeutics, Inc.
Healthcare
|
NEW | 43,853 | $392,484 | 0.08% | |
| ACAD |
Acadia Pharmaceuticals Inc
Healthcare
|
Reduced | 12,967 | $288,645 | 0.06% | |
| SVRA |
Savara Inc
Healthcare
|
NEW | 50,000 | $273,000 | 0.05% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.