Palo Alto Investors LP

Position in ACRS — Aclaris Therapeutics, Inc.

CIK 1306923 PALO ALTO, CA

Position in ACRS

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$6,050,362

+$1,334,174 QoQ

Shares Held

1,613,430

+3.0% QoQ

Ownership

1.16%

of shares outstanding

% of Portfolio

0.94%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2024

9 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

Palo Alto Investors LP holds $530,756,561 across 38 Biotechnology names. ACRS ranks #22 (1.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	INSM	INSMED Inc	415,269	$67,904,786
2	ACAD	Acadia Pharmaceuticals Inc	2,872,695	$63,946,190
3	PTCT	Ptc Therapeutics, Inc.	921,607	$62,789,084
4	BMRN	Biomarin Pharmaceutical Inc	685,182	$38,705,931
5	MIRM	Mirum Pharmaceuticals, Inc.	325,175	$30,039,666
6	DYN	Dyne Therapeutics, Inc.	1,652,972	$29,968,382
7	IRON	Disc Medicine, Inc.	401,719	$25,685,912
8	ANAB	Anaptysbio, Inc	638,161	$23,594,918

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$6,050,362	1,613,430	+3.0%	Shares	Sole	2026-05-15
2025-12-31	$4,716,188	1,566,840	0.0%	Shares	Sole	2026-02-17
2025-09-30	$2,976,996	1,566,840	+12.7%	Shares	Sole	2025-11-14
2025-06-30	$1,973,839	1,390,028	+79.1%	Shares	Sole	2025-08-14
2025-03-31	$1,187,322	776,028	+36.2%	Shares	Sole	2025-05-15
2024-12-31	$1,413,183	569,832	0.0%	Shares	Sole	2025-02-14
2024-09-30	$655,306	569,832	0.0%	Shares	Sole	2024-11-14
2024-06-30	$626,815	569,832	0.0%	Shares	Sole	2024-08-14
2024-03-31	$706,591	569,832	—	Shares	Sole	2024-05-15
No filing history on record for this holder in this stock.