LYRA

Lyra Therapeutics, Inc.

Company with tickers: LYRA

CIK

1327273

CUSIP

55234L204

Shares Outstanding

1,774,882

13F Activity (30d)

3 filings 2 filers

Trades by corporate insiders — officers, directors and holders of more than 10% of the shares — disclosed to the SEC on Forms 3, 4 and 5. Form 4 must be filed within two business days of the trade.

Date	Insider	Role	Type	Shares	Price	Value	After
2026-05-14	Smith W Bradford	See remarks	Other	640	—	—	0
2026-04-01	Cavalier Jason	Principal Financial Officer	Other	667	—	—	517,880
2026-04-01	Palasis Maria	Director, Principal Executive Officer	Other	2,000	—	—	1,094,733
2026-01-06	Palasis Maria	Director, Principal Executive Officer	Sell	1,702	$3.36	$5,726	1,096,733
2026-01-06	Cavalier Jason	Principal Financial Officer	Sell	769	$3.36	$2,587	518,547
2025-11-13	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	3,213	$3.90	$12,531	14,026
2025-11-13	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	28,597	$3.90	$111,531	124,859
2025-11-12	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	7,862	$4.06	$31,915	153,456
2025-11-12	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	883	$4.06	$3,584	17,239
2025-11-11	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	4,783	$4.31	$20,637	161,318
2025-11-11	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	537	$4.31	$2,317	18,122
2025-11-10	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	16,633	$4.54	$75,510	166,101
2025-11-10	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	1,869	$4.54	$8,485	18,659
2025-11-07	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	17,746	$4.75	$84,235	182,734
2025-11-07	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	1,993	$4.75	$9,460	20,528
2025-11-06	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	3,247	$5.18	$16,819	22,521
2025-11-06	PERCEPTIVE ADVISORS LLC	10% Owner	Sell	28,902	$5.18	$149,709	200,480
2025-10-01	Palasis Maria	Director, Principal Executive Officer	Award	3,667	—	—	7,333
2025-07-10	Cavalier Jason	Principal Financial Officer	Sell	684	$8.91	$6,094	519,316
2025-07-10	Palasis Maria	Director, Principal Executive Officer	Sell	1,565	$8.91	$13,944	1,098,435
2025-05-14	TOBIN JAMES R	Director	Award	32,000	—	—	32,000
2025-05-14	MERRIFIELD C ANN	Director	Award	32,000	—	—	32,000
2025-05-14	snyderman nancy lynn MD	Director	Award	32,000	—	—	32,000
2025-05-14	Smith W Bradford	See remarks	Award	32,000	—	—	32,000
2025-01-08	Palasis Maria	Director, Principal Executive Officer	Award	800,000	—	—	1,100,000
2025-01-08	Cavalier Jason	Principal Financial Officer	Award	420,000	—	—	520,000
2024-12-09	Palasis Maria	Director, Principal Executive Officer	Award	183,333	—	—	183,333
2024-12-09	Waksal Harlan	Director	Award	128,333	—	—	0
2024-10-16	Palasis Maria	Director, Principal Executive Officer	Award	300,000	—	—	300,000
2024-10-16	Cavalier Jason	Principal Financial Officer	Award	100,000	—	—	100,000
2024-06-13	MERRIFIELD C ANN	Director	Award	30,000	—	—	30,000
2024-06-13	Smith W Bradford	See remarks	Award	30,000	—	—	30,000
2024-06-13	Poukalov Konstantin	Director	Award	30,000	—	—	30,000
2024-06-13	TOBIN JAMES R	Director	Award	30,000	—	—	30,000
2024-06-13	snyderman nancy lynn MD	Director	Award	30,000	—	—	30,000
2024-06-13	ALTMAN MICHAEL SETH	Director, Chief Business Officer, 10% Owner	Award	30,000	—	—	30,000
2024-03-18	Waksal Harlan	Director	Award	275,000	—	—	536,966
2024-03-18	Palasis Maria	Director, Principal Executive Officer	Award	500,000	—	—	500,000
2024-01-30	Bishop John E	Chief Technology Officer	Award	200,000	—	—	200,000
2024-01-30	Nieman Richard	Chief Medical Officer	Award	200,000	—	—	200,000
2024-01-30	Cavalier Jason	Principal Financial Officer	Award	200,000	—	—	200,000
2023-11-10	Waksal Harlan	Director	Buy	25,000	$2.96	$74,095	261,966
2023-06-30	snyderman nancy lynn MD	Director	Award	20,000	—	—	20,000
2023-06-30	ALTMAN MICHAEL SETH	Director, Chief Business Officer, 10% Owner	Award	20,000	—	—	20,000
2023-06-30	Smith W Bradford	See remarks	Award	20,000	—	—	20,000
2023-06-30	TOBIN JAMES R	Director	Award	20,000	—	—	20,000
2023-06-30	Poukalov Konstantin	Director	Award	20,000	—	—	20,000
2023-06-30	MERRIFIELD C ANN	Director	Award	20,000	—	—	20,000
2023-06-30	ANDERSON EDWARD T	Director, 10% Owner	Award	20,000	—	—	20,000
2023-06-15	Palasis Maria	Director, Principal Executive Officer	Award	150,000	—	—	150,000

Showing 1–50 of 425 transactions