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Equibles

DIMENSIONAL FUND ADVISORS LP

Position in SPRO — Spero Therapeutics, Inc.

CIK 354204 AUSTIN, TX
Back to SPRO Full portfolio

Position in SPRO

as of Jun 30, 2026 · filed Aug 11, 2026
Position Value
$607,350
+$537,694 QoQ
Shares Held
274,820
+823.2% QoQ
Ownership
0.472%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#14
of 59 holders
Holding Since
Mar 2020
24 quarters on record
Voting authority Sole 80% Shared 20% None 0%

Common Shares in SPRO Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

DIMENSIONAL FUND ADVISORS LP holds $6,163,799,259 across 230 Biotechnology names. SPRO ranks #174 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 VRTX
Vertex Pharmaceuticals Inc / Ma
 1,168,956 $580,655,511
2 JAZZ
Jazz Pharmaceuticals plc
 1,713,592 $412,924,262
3 REGN
Regeneron Pharmaceuticals, Inc.
 559,687 $348,987,230
4 INCY
Incyte Corp
 2,280,803 $258,551,825
5 EXEL
Exelixis, Inc.
 4,426,620 $240,852,392
6 BMRN
Biomarin Pharmaceutical Inc
 4,075,714 $233,212,353
7 ROIV
Roivant Sciences Ltd.
 5,230,417 $185,104,455
8 KRYS
Krystal Biotech, Inc.
 476,038 $176,929,041

All Filings in SPRO

Export CSV
24 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $607,350 274,820
2026-03-31 $69,656 29,768
2025-12-31 $69,357 29,768
2025-09-30 $54,508 28,994
2024-12-31 $10,303 10,003
2024-09-30 $13,404 10,003
2024-06-30 $13,003 10,003
2024-03-31 $17,205 10,003
2023-12-31 $14,704 10,003
2023-09-30 $14,221 11,753
2023-06-30 $17,041 11,753
2023-03-31 $17,041 11,753
2022-12-31 $20,332 11,753
2022-09-30 $20,006 10,003
2022-06-30 $211,150 284,956
2022-03-31 $3,540,430 406,946
2021-12-31 $5,943,264 371,222
2021-09-30 $6,068,543 329,633
2021-06-30 $5,227,224 374,443
2021-03-31 $5,041,688 342,506
2020-12-31 $4,851,319 250,197
2020-09-30 $2,578,060 231,009
2020-06-30 $2,897,517 214,155
2020-03-31 $1,606,796 198,861