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Equibles

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

Position in SPRO — Spero Therapeutics, Inc.

CIK 884546 SAN FRANCISCO, CA
Back to SPRO Full portfolio

Position in SPRO

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$63,128
-$3,714 QoQ
Shares Held
28,565
0.0% QoQ
Ownership
0.049%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#34
of 60 holders
Holding Since
Mar 2020
24 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SPRO Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

CHARLES SCHWAB INVESTMENT MANAGEMENT INC holds $7,402,603,842 across 299 Biotechnology names. SPRO ranks #294 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 VRTX
Vertex Pharmaceuticals Inc / Ma
 2,041,282 $1,013,966,007
2 REGN
Regeneron Pharmaceuticals, Inc.
 846,306 $527,705,642
3 RVMD
Revolution Medicines, Inc.
 1,917,025 $359,020,441
4 MRNA
Moderna, Inc.
 4,838,884 $338,867,045
5 ALNY
Alnylam Pharmaceuticals, Inc.
 755,377 $227,391,137
6 INCY
Incyte Corp
 1,692,439 $191,854,884
7 RPRX
Royalty Pharma plc
 3,083,528 $172,893,414
8 CYTK
Cytokinetics Inc
 1,565,781 $133,388,883

All Filings in SPRO

Export CSV
24 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $63,128 28,565
2026-03-31 $66,842 28,565
2025-12-31 $66,556 28,565
2025-09-30 $53,702 28,565
2025-06-30 $82,838 28,565
2025-03-31 $20,566 28,565
2024-12-31 $29,421 28,565
2024-09-30 $38,277 28,565
2024-06-30 $37,134 28,565
2024-03-31 $49,131 28,565
2023-12-31 $41,990 28,565
2023-09-30 $34,563 28,565
2023-06-30 $41,419 28,565
2023-03-31 $41,419 28,565
2022-12-31 $49,417 28,565
2022-03-31 $570,258 65,547
2021-12-31 $1,049,407 65,547
2021-09-30 $1,170,618 63,586
2021-06-30 $844,524 60,496
2021-03-31 $785,429 53,358
2020-12-31 $1,005,003 51,831
2020-09-30 $395,666 35,454
2020-06-30 $479,692 35,454
2020-03-31 $253,421 31,364