TWO SIGMA SECURITIES, LLC
Broker-DealerPosition in ALNY — Alnylam Pharmaceuticals, Inc.
CIK 1450144
NEW YORK, NY
Position in ALNY
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$1,681,252
+$887,812 QoQ
Shares Held
5,585
+221.0% QoQ
Ownership
0.004%
of shares outstanding
% of Portfolio
0.21%
of 13F equity value
Holder Rank
#339
of 764 holders
Holding Since
Mar 2020
20 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in ALNY Over Time
Shares Held
Position Value (USD)
Derivatives in ALNY
reported options exposure · as of Sep 30, 2024CallValue
$1,017,611
CallShares
3,700
PutValue
$935,102
PutShares
3,400
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA SECURITIES, LLC holds $22,449,685 across 103 Biotechnology names. ALNY ranks #2 (7.5% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | REGN |
Regeneron Pharmaceuticals, Inc.
|
5,761 | $3,592,213 | |
| 2 | ALNY |
Alnylam Pharmaceuticals, Inc.
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|
5,585 | $1,681,252 | |
| 3 | BBIO |
BridgeBio Pharma, Inc.
|
17,689 | $1,317,476 | |
| 4 | MDGL |
Madrigal Pharmaceuticals, Inc.
|
2,219 | $1,191,492 | |
| 5 | INSM |
INSMED Inc
|
10,338 | $1,102,237 | |
| 6 | HALO |
Halozyme Therapeutics, Inc.
|
12,525 | $980,331 | |
| 7 | ARWR |
Arrowhead Pharmaceuticals, Inc.
|
11,256 | $917,476 | |
| 8 | AXSM |
Axsome Therapeutics, Inc.
|
3,708 | $907,607 |
All Filings in ALNY
Export CSV
31 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $1,681,252 | 5,585 | Shares | Sole | 2026-08-14 | |
| 2025-09-30 | $793,440 | 1,740 | Shares | Sole | 2025-11-14 | |
| 2025-03-31 | $312,953 | 1,159 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $262,841 | 1,117 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $1,017,611 | 3,700 | Call | Sole | 2024-11-14 | |
| 2024-09-30 | $935,102 | 3,400 | Put | Sole | 2024-11-14 | |
| 2024-06-30 | $5,783,400 | 23,800 | Put | Sole | 2024-08-14 | |
| 2024-06-30 | $13,156,506 | 54,142 | Shares | Sole | 2024-08-14 | |
| 2024-06-30 | $2,430,000 | 10,000 | Call | Sole | 2024-08-14 | |
| 2024-03-31 | $866,810 | 5,800 | Put | Sole | 2024-05-15 | |
| 2024-03-31 | $1,524,390 | 10,200 | Call | Sole | 2024-05-15 | |
| 2023-12-31 | $2,718,022 | 14,200 | Put | Sole | 2024-02-14 | |
| 2023-12-31 | $2,009,805 | 10,500 | Call | Sole | 2024-02-14 | |
| 2023-09-30 | $549,010 | 3,100 | Put | Sole | 2023-11-14 | |
| 2023-09-30 | $354,200 | 2,000 | Call | Sole | 2023-11-14 | |
| 2023-06-30 | $970,783 | 5,111 | Shares | Sole | 2023-08-14 | |
| 2023-06-30 | $303,904 | 1,600 | Call | Sole | 2023-08-14 | |
| 2023-03-31 | $304,686 | 1,521 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $213,885 | 900 | Call | Sole | 2023-02-14 | |
| 2022-12-31 | $947,748 | 3,988 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $280,224 | 1,400 | Call | Sole | 2022-11-14 | |
| 2022-09-30 | $621,897 | 3,107 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $1,646,646 | 11,290 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $685,818 | 4,200 | Call | Sole | 2022-05-16 | |
| 2022-03-31 | $1,225,981 | 7,508 | Shares | Sole | 2022-05-16 | |
| 2022-03-31 | $326,580 | 2,000 | Put | Sole | 2022-05-16 | |
| 2021-12-31 | $360,357 | 2,125 | Shares | Sole | 2022-02-14 | |
| 2021-06-30 | $350,228 | 2,066 | Shares | Sole | 2021-08-16 | |
| 2020-12-31 | $272,937 | 2,100 | Call | Sole | 2021-02-16 | |
| 2020-09-30 | $305,760 | 2,100 | Call | Sole | 2020-11-16 | |
| 2020-03-31 | $511,595 | 4,700 | Put | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||