Squarepoint Ops LLC

CIK

1642575

City

NEW YORK

State / Country

Stock

ALNY — Alnylam Pharmaceuticals, Inc.

Top Portfolio Positions

2,588 positions · $69,761,205,779 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
SPY	Spdr S&P 500 ETF Trust	7,401,017	$4,813,177,395	6.90%
QQQ	Invesco Qqq Trust, Series 1	5,389,200	$3,110,538,456	4.46%
MSFT	Microsoft Corp Technology	5,813,824	$2,152,103,230	3.08%
GOOGL	Alphabet Inc. Communication Services	5,192,225	$1,493,076,221	2.14%
NVDA	Nvidia Corp Technology	8,433,804	$1,470,855,417	2.11%
TSLA	Tesla, Inc. Consumer Cyclical	3,531,361	$1,312,783,451	1.88%
AAPL	Apple Inc. Technology	4,847,643	$1,230,283,316	1.76%
AMZN	Amazon Com Inc Consumer Cyclical	5,177,733	$1,078,366,451	1.55%
MU	Micron Technology Inc Technology	2,521,073	$851,719,302	1.22%
AVGO	Broadcom Inc. Technology	2,521,297	$780,366,634	1.12%

Portfolio Trend

25 quarters · across all stocks

Holdings in ALNY

Compact Export CSV

Shares Held

Position Value (USD)

41 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$22,863,117	69,100	-83.8%	Call	Defined	2026-05-15
2026-03-31	$141,189,839	426,723	+3341.3%	Shares	Defined	2026-05-15
2026-03-31	$4,102,788	12,400	-96.5%	Put	Defined	2026-05-15
2025-12-31	$139,562,822	350,969	+380.1%	Shares	Defined	2026-02-13
2025-12-31	$29,068,215	73,100	+1875.7%	Call	Defined	2026-02-13
2025-12-31	$1,471,305	3,700	-97.5%	Put	Defined	2026-02-13
2025-09-30	$66,377,640	145,565	+713.2%	Shares	Defined	2025-11-14
2025-09-30	$8,162,400	17,900	+110.6%	Call	Defined	2025-11-14
2025-09-30	$3,876,000	8,500	+240.0%	Put	Defined	2025-11-14
2025-06-30	$815,225	2,500	-41.9%	Call	Defined	2025-08-27
2025-06-30	$1,402,187	4,300	+75.8%	Put	Defined	2025-08-27
2025-06-30	$797,616	2,446	-61.0%	Shares	Defined	2025-08-27
2025-03-31	$1,692,485	6,268	+198.5%	Shares	Defined	2025-08-27
2025-03-31	$567,042	2,100	-56.2%	Call	Defined	2025-08-27
2025-03-31	$1,296,096	4,800	-73.8%	Put	Defined	2025-08-27
2024-12-31	$4,306,173	18,300	-85.7%	Put	Defined	2025-02-14
2024-12-31	$30,048,381	127,697	+448.1%	Shares	Defined	2025-02-14
2024-12-31	$5,482,723	23,300	-45.4%	Call	Defined	2025-02-14
2024-09-30	$11,744,056	42,701	+1086.1%	Shares	Defined	2024-11-14
2024-09-30	$990,108	3,600	-55.6%	Put	Defined	2024-11-14
2024-09-30	$2,227,743	8,100	-91.8%	Call	Defined	2024-11-14
2024-06-30	$24,006,942	98,794	+8132.8%	Shares	Defined	2024-08-14
2024-06-30	$291,600	1,200	-94.0%	Put	Defined	2024-08-14
2024-03-31	$2,989,000	20,000	0.0%	Call	Defined	2024-05-15
2024-03-31	$2,989,000	20,000	-96.6%	Put	Defined	2024-05-15
2024-03-31	$86,746,907	580,441	+72.8%	Shares	Defined	2024-05-15
2023-12-31	$64,280,454	335,826	+41.3%	Shares	Defined	2024-02-14
2023-09-30	$42,084,981	237,634	+41.8%	Shares	Defined	2023-11-14
2023-06-30	$31,838,312	167,623	+25.8%	Shares	Defined	2023-08-14
2023-03-31	$26,688,232	133,228	+5931.1%	Shares	Defined	2023-05-15
2022-12-31	$524,968	2,209	-94.1%	Shares	Defined	2023-02-14
2022-09-30	$7,556,040	37,750	-69.8%	Shares	Defined	2022-11-14
2022-06-30	$18,245,835	125,100	+234.2%	Shares	Defined	2022-08-15
2022-03-31	$6,113,251	37,438	+1870.4%	Shares	Defined	2022-05-16
2021-06-30	$322,088	1,900	-85.6%	Put	Defined	2021-08-16
2021-03-31	$1,863,708	13,200	-79.6%	Call	Defined	2021-05-17
2021-03-31	$9,120,874	64,600	+177.2%	Put	Defined	2021-05-17
2020-12-31	$3,029,340	23,308	-15.2%	Shares	Defined	2021-02-16
2020-09-30	$4,002,689	27,491	+777.7%	Shares	Defined	2020-11-16
2020-06-30	$463,880	3,132	-73.3%	Shares	Defined	2020-08-14
2020-03-31	$1,277,463	11,736	—	Shares	Defined	2020-05-15
No 13F history on record for this holder in this stock.