ORBIMED ADVISORS LLC

Position in AMLX — Amylyx Pharmaceuticals, Inc.

CIK 1055951 New York, NY

Position in AMLX

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$3,293,864

-$6,906,790 QoQ

Shares Held

183,400

-75.6% QoQ

Ownership

0.165%

of shares outstanding

% of Portfolio

0.07%

of 13F equity value

Holder Rank

#63

of 205 holders

Holding Since

Mar 2023

6 quarters on record

Voting authority Sole 0% Shared 0% None 100%

Healthcare · as of Jun 30, 2026

ORBIMED ADVISORS LLC holds $67,146,504 across 4 Drug Manufacturers - Specialty & Generic names. AMLX ranks #4 (4.9% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	KNSA	Kiniksa Pharmaceuticals International, plc	420,600	$26,897,370
2	BCRX	Biocryst Pharmaceuticals Inc	1,852,000	$18,520,000
3	BIOA	BioAge Labs, Inc.	752,153	$18,435,270
4	AMLX	Amylyx Pharmaceuticals, Inc. This page	183,400	$3,293,864

6 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$3,293,864	183,400	-75.6%	Shares	Sole	2026-08-14
2025-09-30	$10,200,654	750,600	+139.7%	Shares	Defined	2025-11-14
2025-06-30	$2,007,612	313,200	-10.0%	Shares	Sole	2025-08-14
2025-03-31	$1,231,920	348,000	0.0%	Shares	Sole	2025-05-15
2024-12-31	$1,315,440	348,000	-57.2%	Shares	Sole	2025-02-14
2023-03-31	$23,868,090	813,500	—	Shares	Defined	2023-05-15
No filing history on record for this holder in this stock.