TWO SIGMA SECURITIES, LLC
Broker-DealerPosition in APLS — Apellis Pharmaceuticals, Inc.
CIK 1450144
NEW YORK, NY
Position in APLS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$956,629
+$590,211 QoQ
Shares Held
23,779
+12.3% QoQ
Ownership
0.019%
of shares outstanding
% of Portfolio
0.18%
of 13F equity value
Holder Rank
#178
of 320 holders
Holding Since
Jun 2023
3 quarters on record
Voting authority
Sole 100.ToString("F0")%
Shared 0.ToString("F0")%
None 0.ToString("F0")%
Common Shares in APLS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA SECURITIES, LLC holds $12,820,189 across 97 Biotechnology names. APLS ranks #3 (7.5% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | BMRN |
Biomarin Pharmaceutical Inc
|
22,096 | $1,248,203 | |
| 2 | INCY |
Incyte Corp
|
11,772 | $1,107,980 | |
| 3 | APLS |
Apellis Pharmaceuticals, Inc.
This page
|
23,779 | $956,629 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
1,135 | $876,946 | |
| 5 | TERN |
Terns Pharmaceuticals, Inc.
|
11,908 | $627,789 | |
| 6 | PSTV |
Plus Therapeutics, Inc.
|
142,812 | $580,530 | |
| 7 | ABVX |
Abivax S.A.
|
3,936 | $438,273 | |
| 8 | SYRE |
Spyre Therapeutics, Inc.
|
6,851 | $345,564 |
All Filings in APLS
Export CSV
3 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $956,629 | 23,779 | Shares | Sole | 2026-05-15 | |
| 2025-06-30 | $366,418 | 21,168 | Shares | Sole | 2025-08-14 | |
| 2023-06-30 | $201,968 | 2,217 | Shares | Sole | 2023-08-14 | |
| No filing history on record for this holder in this stock. | ||||||