Opaleye Management Inc.
Top Portfolio Positions
53 positions ·
$763,048,828 total
· as of Mar 31, 2026
| Ticker | Company | Shares | Value (USD) | % of Portfolio | Open |
|---|---|---|---|---|---|
| HROW |
Harrow, Inc.
Healthcare
|
2,832,230 | $99,864,429 | 13.09% | |
| LQDA |
Liquidia Corp
Healthcare
|
2,545,000 | $96,048,300 | 12.59% | |
| ETON |
Eton Pharmaceuticals, Inc.
Healthcare
|
2,860,000 | $70,584,800 | 9.25% | |
| SLGL |
Sol-Gel Technologies Ltd.
Healthcare
|
500,000 | $39,610,000 | 5.19% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
12,600,000 | $38,430,000 | 5.04% | |
| APGE |
Apogee Therapeutics, Inc.
Healthcare
|
390,000 | $32,826,300 | 4.30% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
421,000 | $26,918,740 | 3.53% | |
| URGN |
UroGen Pharma Ltd.
Healthcare
|
1,430,000 | $25,711,400 | 3.37% | |
| CBIO |
Crescent Biopharma, Inc.
Healthcare
|
1,312,615 | $24,112,737 | 3.16% | |
| STOK |
Stoke Therapeutics, Inc.
Healthcare
|
700,000 | $22,792,000 | 2.99% |
Portfolio Trend
25 quarters · across all stocks
Holdings in EWTX
Shares Held
Position Value (USD)
17 quarters on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $15,750,000 | 500,000 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $12,407,500 | 500,000 | Shares | Sole | 2026-04-13 | |
| 2025-09-30 | $8,110,000 | 500,000 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $6,423,900 | 490,000 | Shares | Sole | 2025-08-15 | |
| 2025-03-31 | $8,690,000 | 395,000 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $12,816,000 | 480,000 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $13,945,525 | 522,500 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $10,445,800 | 580,000 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $12,129,600 | 665,000 | Shares | Sole | 2024-05-29 | |
| 2023-12-31 | $7,647,060 | 699,000 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $5,016,070 | 875,405 | Shares | Sole | 2023-11-15 | |
| 2023-06-30 | $6,316,250 | 815,000 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $5,002,500 | 750,000 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $5,465,916 | 611,400 | Shares | Sole | 2023-02-10 | |
| 2022-09-30 | $6,248,400 | 635,000 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $3,593,144 | 451,400 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $2,939,100 | 303,000 | Shares | Sole | 2022-05-16 | |
| No 13F history on record for this holder in this stock. | ||||||