Paradigm Biocapital Advisors LP

CIK

1855655

City

NEW YORK

State / Country

NY

Stock

EWTX — Edgewise Therapeutics, Inc.

Top Portfolio Positions

35 positions · $4,934,767,608 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
ACLX	Arcellx, Inc. Healthcare	5,774,016	$662,972,517	13.43%
RVMD	Revolution Medicines, Inc. Healthcare	6,655,703	$647,267,116	13.12%
NUVL	Nuvalent, Inc. Healthcare	5,324,433	$545,488,160	11.05%
PCVX	Vaxcyte, Inc. Healthcare	4,793,020	$278,522,392	5.64%
EWTX	Edgewise Therapeutics, Inc. Healthcare	7,365,038	$231,998,697	4.70%
GMAB	Genmab A/S Healthcare	7,967,836	$213,777,039	4.33%
INSM	INSMED Inc Healthcare	1,254,488	$205,133,877	4.16%
TARS	Tarsus Pharmaceuticals, Inc. Healthcare	2,562,154	$179,735,103	3.64%
BLTE	Belite Bio, Inc Healthcare	1,114,784	$177,741,160	3.60%
ERAS	Erasca, Inc. Healthcare	10,392,702	$168,153,918	3.41%

Portfolio Trend

18 quarters · across all stocks

Holdings in EWTX

Compact Export CSV

Shares Held

Position Value (USD)

12 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$231,998,697	7,365,038	+12.6%	Shares	Sole	2026-05-15
2025-12-31	$162,320,126	6,541,210	0.0%	Shares	Sole	2026-02-17
2025-12-31	$162,320,126	6,541,210	+6.0%	Shares	Sole	2026-02-17
2025-09-30	$100,079,524	6,170,131	+0.5%	Shares	Sole	2025-11-14
2025-06-30	$80,526,129	6,142,344	+1128.5%	Shares	Sole	2025-08-14
2025-03-31	$11,000,000	500,000	-88.6%	Call	Sole	2025-05-15
2025-03-31	$96,680,232	4,394,556	-7.3%	Shares	Sole	2025-05-15
2025-01-27	$131,979,172	4,738,929	+5.5%	Shares	Sole	2025-02-03
2024-12-31	$119,987,904	4,493,929	+61.1%	Shares	Sole	2025-02-14
2024-09-30	$74,443,000	2,789,172	+19.9%	Shares	Sole	2024-11-14
2024-06-30	$41,881,336	2,325,449	-4.9%	Shares	Sole	2024-08-14
2024-03-31	$44,621,843	2,446,373	—	Shares	Sole	2024-05-15
No 13F history on record for this holder in this stock.