ORBIMED ADVISORS LLC

CIK

1055951

City

New York

State / Country

NY

Stock

GH — Guardant Health, Inc.

Top Portfolio Positions

107 positions · $5,411,268,746 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
MYGN	Myriad Genetics Inc Healthcare	125,000,000	$562,500,000	10.39%
EWTX	Edgewise Therapeutics, Inc. Healthcare	15,518,492	$488,832,498	9.03%
ELVN	Enliven Therapeutics, Inc. Healthcare	7,959,538	$312,013,889	5.77%
RCEL	AVITA Medical, Inc. Healthcare	82,010,995	$303,440,681	5.61%
MDXH	MDxHealth SA Healthcare	124,306,000	$285,903,800	5.28%
LLY	ELI LILLY & Co Healthcare	236,800	$217,801,536	4.02%
BSX	Boston Scientific Corp Healthcare	2,382,100	$149,476,775	2.76%
SION	Sionna Therapeutics, Inc. Healthcare	3,530,702	$141,545,843	2.62%
AZN	Astrazeneca PLC Healthcare	670,200	$132,176,844	2.44%
MBX	MBX Biosciences, Inc. Healthcare	3,637,887	$108,590,926	2.01%

Portfolio Trend

25 quarters · across all stocks

Holdings in GH

Compact Export CSV

Shares Held

Position Value (USD)

11 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$40,199,424	435,200	-56.1%	Shares	Defined	2026-05-15
2022-09-30	$53,420,892	992,400	+1884.8%	Shares	Sole	2022-11-14
2022-06-30	$2,017,000	50,000	-95.2%	Call	Defined	2022-08-15
2022-06-30	$41,687,356	1,033,400	-22.0%	Shares	Defined	2022-08-15
2022-03-31	$87,794,496	1,325,400	+8.0%	Shares	Defined	2022-05-16
2021-12-31	$122,764,548	1,227,400	0.0%	Shares	Defined	2022-02-14
2021-09-30	$153,437,274	1,227,400	0.0%	Shares	Defined	2021-11-15
2021-06-30	$152,430,806	1,227,400	+25.6%	Shares	Defined	2021-08-16
2021-03-31	$149,200,110	977,400	+81.6%	Shares	Defined	2021-05-17
2020-12-31	$69,363,216	538,200	+248.8%	Shares	Defined	2021-02-16
2020-09-30	$17,247,654	154,300	—	Shares	Defined	2020-11-16
No 13F history on record for this holder in this stock.