ORBIMED ADVISORS LLC

CIK

1055951

City

New York

State / Country

NY

Stock

HRTX — Heron Therapeutics, Inc. /De/

Top Portfolio Positions

107 positions · $5,411,268,746 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
MYGN	Myriad Genetics Inc Healthcare	125,000,000	$562,500,000	10.39%
EWTX	Edgewise Therapeutics, Inc. Healthcare	15,518,492	$488,832,498	9.03%
ELVN	Enliven Therapeutics, Inc. Healthcare	7,959,538	$312,013,889	5.77%
RCEL	AVITA Medical, Inc. Healthcare	82,010,995	$303,440,681	5.61%
MDXH	MDxHealth SA Healthcare	124,306,000	$285,903,800	5.28%
LLY	ELI LILLY & Co Healthcare	236,800	$217,801,536	4.02%
BSX	Boston Scientific Corp Healthcare	2,382,100	$149,476,775	2.76%
SION	Sionna Therapeutics, Inc. Healthcare	3,530,702	$141,545,843	2.62%
AZN	Astrazeneca PLC Healthcare	670,200	$132,176,844	2.44%
MBX	MBX Biosciences, Inc. Healthcare	3,637,887	$108,590,926	2.01%

Portfolio Trend

25 quarters · across all stocks

Holdings in HRTX

Compact Export CSV

Shares Held

Position Value (USD)

12 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$7,853,552	9,816,940	+50.7%	Shares	Defined	2026-05-15
2024-06-30	$22,795,031	6,512,866	-35.6%	Shares	Defined	2024-08-14
2024-03-31	$28,008,993	10,111,550	+70.6%	Shares	Defined	2024-05-15
2023-12-31	$10,078,604	5,928,591	+638.6%	Shares	Defined	2024-02-14
2023-09-30	$826,781	802,700	0.0%	Shares	Sole	2023-11-14
2023-06-30	$931,132	802,700	0.0%	Shares	Sole	2023-08-14
2023-03-31	$1,212,077	802,700	-28.5%	Shares	Sole	2023-05-15
2022-09-30	$4,739,060	1,123,000	-5.8%	Shares	Sole	2022-11-14
2020-12-31	$25,231,379	1,191,846	0.0%	Shares	Sole	2021-02-16
2020-09-30	$17,663,157	1,191,846	+80.5%	Shares	Sole	2020-11-16
2020-06-30	$9,714,778	660,420	+22.9%	Shares	Sole	2020-08-14
2020-03-31	$6,309,310	537,420	—	Shares	Sole	2020-05-15
No 13F history on record for this holder in this stock.