SUSQUEHANNA INTERNATIONAL GROUP, LLP
Position in IONS — Ionis Pharmaceuticals Inc
CIK 1446194
BALA CYNWYD, PA
Position in IONS
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$304,394
-$623,643 QoQ
Shares Held
3,839
-68.9% QoQ
Ownership
0.002%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#342
of 514 holders
Holding Since
Mar 2020
26 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in IONS Over Time
Shares Held
Position Value (USD)
Derivatives in IONS
reported options exposure · as of Jun 30, 2026CallValue
$103,108,716
CallShares
1,300,400
PutValue
$65,184,309
PutShares
822,100
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026SUSQUEHANNA INTERNATIONAL GROUP, LLP holds $1,653,301,875 across 349 Biotechnology names. IONS ranks #194 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ABVX |
Abivax S.A.
|
1,053,896 | $140,442,180 | |
| 2 | CYTK |
Cytokinetics Inc
|
1,549,458 | $131,998,327 | |
| 3 | REGN |
Regeneron Pharmaceuticals, Inc.
|
180,219 | $112,373,755 | |
| 4 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
294,460 | $88,641,293 | |
| 5 | MDGL |
Madrigal Pharmaceuticals, Inc.
|
148,610 | $79,796,139 | |
| 6 | INSM |
INSMED Inc
|
729,354 | $77,763,723 | |
| 7 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
144,174 | $71,615,550 | |
| 8 | AGIO |
Agios Pharmaceuticals, Inc.
|
1,375,558 | $51,046,957 |
All Filings in IONS
Export CSV
50 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $65,184,309 | 822,100 | Put | Other | 2026-08-14 | |
| 2026-06-30 | $304,394 | 3,839 | Shares | Other | 2026-08-14 | |
| 2026-06-30 | $103,108,716 | 1,300,400 | Call | Other | 2026-08-14 | |
| 2026-03-31 | $56,753,022 | 755,800 | Call | Other | 2026-05-15 | |
| 2026-03-31 | $34,113,387 | 454,300 | Put | Other | 2026-05-15 | |
| 2026-03-31 | $928,037 | 12,359 | Shares | Other | 2026-05-15 | |
| 2025-12-31 | $2,571,391 | 32,504 | Shares | Other | 2026-02-17 | |
| 2025-12-31 | $23,108,031 | 292,100 | Put | Other | 2026-02-17 | |
| 2025-12-31 | $41,414,085 | 523,500 | Call | Other | 2026-02-17 | |
| 2025-09-30 | $13,522,314 | 206,700 | Put | Other | 2025-11-14 | |
| 2025-09-30 | $32,710,000 | 500,000 | Call | Other | 2025-11-14 | |
| 2025-09-30 | $27,538,549 | 420,950 | Shares | Other | 2025-11-14 | |
| 2025-06-30 | $3,844,323 | 97,300 | Put | Other | 2025-08-14 | |
| 2025-06-30 | $17,013,006 | 430,600 | Call | Other | 2025-08-14 | |
| 2025-03-31 | $2,166,537 | 71,811 | Shares | Other | 2025-05-14 | |
| 2025-03-31 | $5,382,328 | 178,400 | Call | Other | 2025-05-14 | |
| 2025-03-31 | $2,911,405 | 96,500 | Put | Other | 2025-05-14 | |
| 2024-12-31 | $4,862,936 | 139,100 | Call | Other | 2025-02-14 | |
| 2024-12-31 | $911,197 | 26,064 | Shares | Other | 2025-02-14 | |
| 2024-12-31 | $3,646,328 | 104,300 | Put | Other | 2025-02-14 | |
| 2024-09-30 | $2,351,522 | 58,700 | Put | Defined | 2024-11-14 | |
| 2024-09-30 | $2,292,994 | 57,239 | Shares | Defined | 2024-11-14 | |
| 2024-09-30 | $3,296,938 | 82,300 | Call | Defined | 2024-11-14 | |
| 2024-06-30 | $18,506,378 | 388,300 | Call | Defined | 2024-08-15 | |
| 2024-06-30 | $4,568,591 | 95,858 | Shares | Defined | 2024-08-15 | |
| 2024-06-30 | $5,800,222 | 121,700 | Put | Defined | 2024-08-15 | |
| 2024-03-31 | $5,787,225 | 133,500 | Call | Defined | 2024-05-07 | |
| 2024-03-31 | $8,297,190 | 191,400 | Put | Defined | 2024-05-07 | |
| 2024-03-31 | $6,028,293 | 139,061 | Shares | Defined | 2024-05-07 | |
| 2023-12-31 | $2,738,588 | 54,133 | Shares | Defined | 2024-02-14 | |
| 2023-12-31 | $7,927,453 | 156,700 | Put | Defined | 2024-02-14 | |
| 2023-12-31 | $21,687,933 | 428,700 | Call | Defined | 2024-02-14 | |
| 2023-09-30 | $4,025,200 | 88,739 | Shares | Defined | 2023-11-14 | |
| 2023-09-30 | $11,575,872 | 255,200 | Call | Defined | 2023-11-14 | |
| 2023-09-30 | $5,270,832 | 116,200 | Put | Defined | 2023-11-14 | |
| 2023-06-30 | $6,873,180 | 167,516 | Shares | Defined | 2023-08-11 | |
| 2023-06-30 | $5,912,423 | 144,100 | Call | Defined | 2023-08-11 | |
| 2023-06-30 | $6,072,440 | 148,000 | Put | Defined | 2023-08-11 | |
| 2023-03-31 | $1,998,580 | 55,920 | Shares | Defined | 2023-05-16 | |
| 2023-03-31 | $5,328,834 | 149,100 | Call | Defined | 2023-05-16 | |
| 2023-03-31 | $1,454,618 | 40,700 | Put | Defined | 2023-05-16 | |
| 2022-12-31 | $2,500,374 | 66,200 | Put | Defined | 2023-02-14 | |
| 2022-12-31 | $3,663,690 | 97,000 | Call | Defined | 2023-02-14 | |
| 2022-12-31 | $2,185,825 | 57,872 | Shares | Defined | 2023-02-14 | |
| 2022-09-30 | $3,618,014 | 81,800 | Put | Defined | 2022-11-14 | |
| 2022-09-30 | $1,807,680 | 40,870 | Shares | Defined | 2022-11-14 | |
| 2022-09-30 | $5,798,553 | 131,100 | Call | Defined | 2022-11-14 | |
| 2022-06-30 | $1,390,212 | 37,553 | Shares | Defined | 2022-08-15 | |
| 2022-06-30 | $3,435,456 | 92,800 | Put | Defined | 2022-08-15 | |
| 2022-06-30 | $6,126,810 | 165,500 | Call | Defined | 2022-08-15 | |
| No filing history on record for this holder in this stock. | ||||||