SUSQUEHANNA INTERNATIONAL GROUP, LLP
Position in IONS — Ionis Pharmaceuticals Inc
CIK 1446194
BALA CYNWYD, PA
Position in IONS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$928,037
-$1,643,354 QoQ
Shares Held
12,359
-62.0% QoQ
Ownership
0.007%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 100.ToString("F0")%
Shared 0.ToString("F0")%
None 0.ToString("F0")%
Common Shares in IONS Over Time
Shares Held
Position Value (USD)
Derivatives in IONS
reported options exposure · as of Mar 31, 2026CallValue
$56,753,022
CallShares
755,800
PutValue
$34,113,387
PutShares
454,300
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026SUSQUEHANNA INTERNATIONAL GROUP, LLP holds $1,176,415,994 across 355 Biotechnology names. IONS ranks #178 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | CYTK |
Cytokinetics Inc
|
898,951 | $59,249,860 | |
| 2 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
174,268 | $57,660,053 | |
| 3 | AGIO |
Agios Pharmaceuticals, Inc.
|
1,344,953 | $45,499,759 | |
| 4 | ABVX |
Abivax S.A.
|
381,282 | $42,455,750 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
398,943 | $29,625,507 | |
| 6 | INSM |
INSMED Inc
|
173,630 | $28,391,977 | |
| 7 | CRSP |
CRISPR Therapeutics AG
|
593,406 | $28,228,323 | |
| 8 | TERN |
Terns Pharmaceuticals, Inc.
|
521,571 | $27,497,223 |
All Filings in IONS
Export CSV
50 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $56,753,022 | 755,800 | Call | Other | 2026-05-15 | |
| 2026-03-31 | $34,113,387 | 454,300 | Put | Other | 2026-05-15 | |
| 2026-03-31 | $928,037 | 12,359 | Shares | Other | 2026-05-15 | |
| 2025-12-31 | $2,571,391 | 32,504 | Shares | Other | 2026-02-17 | |
| 2025-12-31 | $23,108,031 | 292,100 | Put | Other | 2026-02-17 | |
| 2025-12-31 | $41,414,085 | 523,500 | Call | Other | 2026-02-17 | |
| 2025-09-30 | $13,522,314 | 206,700 | Put | Other | 2025-11-14 | |
| 2025-09-30 | $32,710,000 | 500,000 | Call | Other | 2025-11-14 | |
| 2025-09-30 | $27,538,549 | 420,950 | Shares | Other | 2025-11-14 | |
| 2025-06-30 | $3,844,323 | 97,300 | Put | Other | 2025-08-14 | |
| 2025-06-30 | $17,013,006 | 430,600 | Call | Other | 2025-08-14 | |
| 2025-03-31 | $2,166,537 | 71,811 | Shares | Other | 2025-05-14 | |
| 2025-03-31 | $5,382,328 | 178,400 | Call | Other | 2025-05-14 | |
| 2025-03-31 | $2,911,405 | 96,500 | Put | Other | 2025-05-14 | |
| 2024-12-31 | $4,862,936 | 139,100 | Call | Other | 2025-02-14 | |
| 2024-12-31 | $911,197 | 26,064 | Shares | Other | 2025-02-14 | |
| 2024-12-31 | $3,646,328 | 104,300 | Put | Other | 2025-02-14 | |
| 2024-09-30 | $2,351,522 | 58,700 | Put | Defined | 2024-11-14 | |
| 2024-09-30 | $2,292,994 | 57,239 | Shares | Defined | 2024-11-14 | |
| 2024-09-30 | $3,296,938 | 82,300 | Call | Defined | 2024-11-14 | |
| 2024-06-30 | $18,506,378 | 388,300 | Call | Defined | 2024-08-15 | |
| 2024-06-30 | $4,568,591 | 95,858 | Shares | Defined | 2024-08-15 | |
| 2024-06-30 | $5,800,222 | 121,700 | Put | Defined | 2024-08-15 | |
| 2024-03-31 | $5,787,225 | 133,500 | Call | Defined | 2024-05-07 | |
| 2024-03-31 | $8,297,190 | 191,400 | Put | Defined | 2024-05-07 | |
| 2024-03-31 | $6,028,293 | 139,061 | Shares | Defined | 2024-05-07 | |
| 2023-12-31 | $2,738,588 | 54,133 | Shares | Defined | 2024-02-14 | |
| 2023-12-31 | $7,927,453 | 156,700 | Put | Defined | 2024-02-14 | |
| 2023-12-31 | $21,687,933 | 428,700 | Call | Defined | 2024-02-14 | |
| 2023-09-30 | $4,025,200 | 88,739 | Shares | Defined | 2023-11-14 | |
| 2023-09-30 | $11,575,872 | 255,200 | Call | Defined | 2023-11-14 | |
| 2023-09-30 | $5,270,832 | 116,200 | Put | Defined | 2023-11-14 | |
| 2023-06-30 | $6,873,180 | 167,516 | Shares | Defined | 2023-08-11 | |
| 2023-06-30 | $5,912,423 | 144,100 | Call | Defined | 2023-08-11 | |
| 2023-06-30 | $6,072,440 | 148,000 | Put | Defined | 2023-08-11 | |
| 2023-03-31 | $1,998,580 | 55,920 | Shares | Defined | 2023-05-16 | |
| 2023-03-31 | $5,328,834 | 149,100 | Call | Defined | 2023-05-16 | |
| 2023-03-31 | $1,454,618 | 40,700 | Put | Defined | 2023-05-16 | |
| 2022-12-31 | $2,500,374 | 66,200 | Put | Defined | 2023-02-14 | |
| 2022-12-31 | $3,663,690 | 97,000 | Call | Defined | 2023-02-14 | |
| 2022-12-31 | $2,185,825 | 57,872 | Shares | Defined | 2023-02-14 | |
| 2022-09-30 | $3,618,014 | 81,800 | Put | Defined | 2022-11-14 | |
| 2022-09-30 | $1,807,680 | 40,870 | Shares | Defined | 2022-11-14 | |
| 2022-09-30 | $5,798,553 | 131,100 | Call | Defined | 2022-11-14 | |
| 2022-06-30 | $1,390,212 | 37,553 | Shares | Defined | 2022-08-15 | |
| 2022-06-30 | $3,435,456 | 92,800 | Put | Defined | 2022-08-15 | |
| 2022-06-30 | $6,126,810 | 165,500 | Call | Defined | 2022-08-15 | |
| 2022-03-31 | $4,804,088 | 129,700 | Put | Defined | 2022-05-16 | |
| 2022-03-31 | $4,918,912 | 132,800 | Call | Defined | 2022-05-16 | |
| 2022-03-31 | $1,841,851 | 49,726 | Shares | Defined | 2022-05-16 | |
| No filing history on record for this holder in this stock. | ||||||