Position in IRWD
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$19,181,134
-$1,346,314 QoQ
Shares Held
4,556,089
-22.1% QoQ
Ownership
2.76%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
#12
of 212 holders
Holding Since
Mar 2020
24 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in IRWD Over Time
Shares Held
Position Value (USD)
Position in Drug Manufacturers - Specialty & Generic
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $775,744,366 across 48 Drug Manufacturers - Specialty & Generic names. IRWD ranks #8 (2.5% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | NBIX |
Neurocrine Biosciences Inc
|
2,076,260 | $349,932,860 | |
| 2 | BCRX |
Biocryst Pharmaceuticals Inc
|
6,775,349 | $67,753,490 | |
| 3 | SUPN |
Supernus Pharmaceuticals, Inc.
|
1,184,378 | $55,085,420 | |
| 4 | ALKS |
Alkermes plc.
|
1,038,311 | $54,407,496 | |
| 5 | KNSA |
Kiniksa Pharmaceuticals International, plc
|
561,480 | $35,906,646 | |
| 6 | ZTS |
Zoetis Inc.
|
386,428 | $27,768,716 | |
| 7 | LQDA |
Liquidia Corp
|
266,829 | $21,274,276 | |
| 8 | IRWD |
Ironwood Pharmaceuticals Inc
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|
4,556,089 | $19,181,134 |
All Filings in IRWD
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24 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $19,181,134 | 4,556,089 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $20,527,448 | 5,848,276 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $9,615,300 | 2,853,205 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $3,320,209 | 2,534,511 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,980,412 | 2,750,573 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $1,803,978 | 1,227,196 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $3,824,986 | 863,428 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $3,670,767 | 890,963 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $5,982,712 | 917,594 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $10,349,509 | 1,188,233 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $6,702,089 | 585,847 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $13,425,789 | 1,394,163 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $28,192,276 | 2,649,650 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $16,034,804 | 1,524,221 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $19,634,259 | 1,584,686 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $1,722,422 | 166,257 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $9,909,965 | 859,494 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $11,182,211 | 888,888 | Shares | Sole | 2022-05-16 | |
| 2021-09-30 | $4,422,560 | 338,634 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $3,242,158 | 251,916 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $5,160,542 | 461,587 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $7,892,757 | 692,955 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $1,243,011 | 138,266 | Shares | Sole | 2020-11-16 | |
| 2020-03-31 | $2,638,020 | 261,449 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||