SUSQUEHANNA INTERNATIONAL GROUP, LLP
Position in KPTI — Karyopharm Therapeutics Inc.
CIK 1446194
BALA CYNWYD, PA
Position in KPTI
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$0
-$134,448 QoQ
Shares Held
0
-100.0% QoQ
Ownership
0.000%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
26 quarters on record
Common Shares in KPTI Over Time
Shares Held
Position Value (USD)
Derivatives in KPTI
reported options exposure · as of Jun 30, 2026CallValue
$4,736,496
CallShares
484,800
PutValue
$594,993
PutShares
60,900
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026SUSQUEHANNA INTERNATIONAL GROUP, LLP holds $1,653,301,875 across 349 Biotechnology names.
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ABVX |
Abivax S.A.
|
1,053,896 | $140,442,180 | |
| 2 | CYTK |
Cytokinetics Inc
|
1,549,458 | $131,998,327 | |
| 3 | REGN |
Regeneron Pharmaceuticals, Inc.
|
180,219 | $112,373,755 | |
| 4 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
294,460 | $88,641,293 | |
| 5 | MDGL |
Madrigal Pharmaceuticals, Inc.
|
148,610 | $79,796,139 | |
| 6 | INSM |
INSMED Inc
|
729,354 | $77,763,723 | |
| 7 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
144,174 | $71,615,550 | |
| 8 | AGIO |
Agios Pharmaceuticals, Inc.
|
1,375,558 | $51,046,957 |
All Filings in KPTI
Export CSV
50 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $4,736,496 | 484,800 | Call | Other | 2026-08-14 | |
| 2026-06-30 | $594,993 | 60,900 | Put | Other | 2026-08-14 | |
| 2026-03-31 | $2,372,263 | 425,900 | Put | Other | 2026-05-15 | |
| 2026-03-31 | $4,818,050 | 865,000 | Call | Other | 2026-05-15 | |
| 2026-03-31 | $134,448 | 24,138 | Shares | Other | 2026-05-15 | |
| 2025-12-31 | $2,695,968 | 366,300 | Put | Other | 2026-02-17 | |
| 2025-12-31 | $1,087,057 | 147,698 | Shares | Other | 2026-02-17 | |
| 2025-12-31 | $2,361,824 | 320,900 | Call | Other | 2026-02-17 | |
| 2025-09-30 | $777,606 | 118,900 | Call | Other | 2025-11-14 | |
| 2025-09-30 | $231,117 | 35,339 | Shares | Other | 2025-11-14 | |
| 2025-09-30 | $835,812 | 127,800 | Put | Other | 2025-11-14 | |
| 2025-06-30 | $71,546 | 16,600 | Call | Other | 2025-08-14 | |
| 2025-03-31 | $41,140 | 11,000 | Put | Other | 2025-05-14 | |
| 2025-03-31 | $238,612 | 63,800 | Call | Other | 2025-05-14 | |
| 2025-03-31 | $43,189 | 11,548 | Shares | Other | 2025-05-14 | |
| 2024-12-31 | $16,021 | 23,700 | Put | Other | 2025-02-14 | |
| 2024-12-31 | $448,961 | 664,145 | Shares | Other | 2025-02-14 | |
| 2024-12-31 | $74,495 | 110,200 | Call | Other | 2025-02-14 | |
| 2024-09-30 | $152,139 | 183,300 | Call | Defined | 2024-11-14 | |
| 2024-09-30 | $251,114 | 302,548 | Shares | Defined | 2024-11-14 | |
| 2024-09-30 | $25,481 | 30,700 | Put | Defined | 2024-11-14 | |
| 2024-06-30 | $384,935 | 443,474 | Shares | Defined | 2024-08-15 | |
| 2024-06-30 | $54,597 | 62,900 | Put | Defined | 2024-08-15 | |
| 2024-06-30 | $212,486 | 244,800 | Call | Defined | 2024-08-15 | |
| 2024-03-31 | $216,232 | 143,200 | Put | Defined | 2024-05-07 | |
| 2024-03-31 | $125,783 | 83,300 | Call | Defined | 2024-05-07 | |
| 2024-03-31 | $115,664 | 76,599 | Shares | Defined | 2024-05-07 | |
| 2023-12-31 | $67,985 | 78,596 | Shares | Defined | 2024-02-14 | |
| 2023-12-31 | $49,132 | 56,800 | Call | Defined | 2024-02-14 | |
| 2023-09-30 | $146,060 | 109,000 | Put | Defined | 2023-11-14 | |
| 2023-09-30 | $75,576 | 56,400 | Call | Defined | 2023-11-14 | |
| 2023-09-30 | $184,663 | 137,809 | Shares | Defined | 2023-11-14 | |
| 2023-06-30 | $159,322 | 89,007 | Shares | Defined | 2023-08-11 | |
| 2023-06-30 | $103,104 | 57,600 | Put | Defined | 2023-08-11 | |
| 2023-06-30 | $88,605 | 49,500 | Call | Defined | 2023-08-11 | |
| 2023-03-31 | $1,148,265 | 295,184 | Shares | Defined | 2023-05-16 | |
| 2023-03-31 | $303,031 | 77,900 | Call | Defined | 2023-05-16 | |
| 2023-03-31 | $287,860 | 74,000 | Put | Defined | 2023-05-16 | |
| 2022-12-31 | $298,860 | 87,900 | Call | Defined | 2023-02-14 | |
| 2022-12-31 | $676,940 | 199,100 | Put | Defined | 2023-02-14 | |
| 2022-12-31 | $867,656 | 255,193 | Shares | Defined | 2023-02-14 | |
| 2022-09-30 | $1,321,866 | 242,100 | Put | Defined | 2022-11-14 | |
| 2022-09-30 | $808,080 | 148,000 | Call | Defined | 2022-11-14 | |
| 2022-09-30 | $2,139,866 | 391,917 | Shares | Defined | 2022-11-14 | |
| 2022-06-30 | $1,271,530 | 281,936 | Shares | Defined | 2022-08-15 | |
| 2022-06-30 | $1,011,593 | 224,300 | Put | Defined | 2022-08-15 | |
| 2022-06-30 | $1,183,424 | 262,400 | Call | Defined | 2022-08-15 | |
| 2022-03-31 | $4,382,939 | 594,700 | Call | Defined | 2022-05-16 | |
| 2022-03-31 | $1,894,090 | 257,000 | Put | Defined | 2022-05-16 | |
| 2022-03-31 | $2,071,920 | 281,129 | Shares | Defined | 2022-05-16 | |
| No filing history on record for this holder in this stock. | ||||||