STATE STREET CORP

Position in KPTI — Karyopharm Therapeutics Inc.

CIK 93751 BOSTON, MA

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Position in KPTI

as of Jun 30, 2026 · filed Aug 7, 2026 Compact

Position Value

$3,184,932

+$2,735,200 QoQ

Shares Held

325,991

+303.7% QoQ

Ownership

1.44%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#17

of 96 holders

Holding Since

Mar 2020

26 quarters on record

Voting authority Sole 31% Shared 0% None 69%

Common Shares in KPTI Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

STATE STREET CORP holds $36,881,619,425 across 411 Biotechnology names. KPTI ranks #245 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	11,871,459	$5,896,909,829
2	REGN	Regeneron Pharmaceuticals, Inc.	4,834,688	$3,014,621,355
3	INCY	Incyte Corp	9,722,336	$1,102,124,008
4	MRNA	Moderna, Inc.	15,726,193	$1,101,305,295
5	ALNY	Alnylam Pharmaceuticals, Inc.	3,555,689	$1,070,369,059
6	RVMD	Revolution Medicines, Inc.	4,897,051	$917,119,711
7	RPRX	Royalty Pharma plc	12,338,229	$691,804,500
8	INSM	INSMED Inc	6,052,174	$645,282,791

All Filings in KPTI

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26 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$3,184,932	325,991	+303.7%	Shares	Defined	2026-08-07
2026-03-31	$449,732	80,742	+37.0%	Shares	Defined	2026-05-15
2025-12-31	$433,813	58,942	+27.2%	Shares	Defined	2026-02-13
2025-09-30	$303,076	46,342	+39.2%	Shares	Defined	2025-11-14
2025-06-30	$143,501	33,295	+12.9%	Shares	Defined	2025-08-14
2025-03-31	$110,311	29,495	-93.3%	Shares	Defined	2025-05-15
2024-12-31	$299,136	442,510	+8.1%	Shares	Defined	2025-02-14
2024-09-30	$339,893	409,510	-9.8%	Shares	Defined	2024-11-14
2024-06-30	$393,907	453,810	-80.1%	Shares	Defined	2024-08-14
2024-03-31	$3,451,539	2,285,788	+11.3%	Shares	Defined	2024-05-15
2023-12-31	$1,776,513	2,053,773	+0.5%	Shares	Defined	2024-02-14
2023-09-30	$2,737,626	2,043,005	-7.7%	Shares	Defined	2023-11-14
2023-06-30	$3,960,136	2,212,367	-78.3%	Shares	Defined	2023-08-14
2023-03-31	$39,584,597	10,175,989	+22.8%	Shares	Defined	2023-05-15
2022-12-31	$28,175,922	8,287,036	-8.0%	Shares	Defined	2023-05-15
2022-09-30	$49,196,450	9,010,339	-13.0%	Shares	Defined	2022-11-15
2022-06-30	$46,732,660	10,362,009	-5.5%	Shares	Defined	2022-08-15
2022-03-31	$80,824,586	10,966,701	+98.9%	Shares	Defined	2022-05-16
2021-12-31	$35,452,962	5,513,680	-31.3%	Shares	Defined	2022-02-14
2021-09-30	$46,676,394	8,019,999	+37.9%	Shares	Defined	2021-11-15
2021-06-30	$60,026,785	5,816,549	+9.1%	Shares	Defined	2021-08-16
2021-03-31	$56,095,585	5,332,280	-0.1%	Shares	Defined	2021-07-09
2020-12-31	$82,661,017	5,339,859	+11.5%	Shares	Defined	2021-02-16
2020-09-30	$69,919,020	4,788,974	+4.1%	Shares	Defined	2020-11-10
2020-06-30	$87,104,056	4,598,947	+41.6%	Shares	Defined	2020-08-14
2020-03-31	$62,384,225	3,247,487	—	Shares	Defined	2020-06-19
No filing history on record for this holder in this stock.