KPTI · Karyopharm Therapeutics Inc.

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$6.86 -0.24 (-3.31%)

Market Cap

$160.68M

22.66M

Options Chain

15-min delayed Underlying $6.86 · today Options Calculator

Positioning

Aug 21, 2026 · 23 days to expiry · 16 contracts

Put / call OI

0.27

Call-heavy positioning

Open interest

30,058

contracts outstanding

Volume

150

traded today

Max pain

$7.50

$0.65 above spot

ATM implied vol

356.2%

market's expected move

Open interest by strike

Calls Puts

2.5

7.5

12.5

17.5

Chain

Click any strike for greeks, breakeven and the calculator

Expiry

Aug 21 23d Sep 18 51d Nov 20 114d Jan 15 170d Feb 19 205d Jan 21 541d

Calls						Puts
OI	Vol	IV	Δ	Last	Strike	Last	Δ	IV	Vol	OI
47	5	378.6%	0.942	$6.47		$0.15	-0.045	318.7%	12	3.1k
Call · $2.5 In the money Last $6.47 Breakeven $8.97 Implied vol 378.6% Delta 0.942 ≈94% ITM Gamma 0.018 Theta -0.017 Vega 0.002 Open interest 47 Model this call Put · $2.5 Last $0.15 Breakeven $2.35 Implied vol 318.7% Delta -0.045 ≈5% ITM Gamma 0.017 Theta -0.012 Vega 0.002 Open interest 3.1k Model this put
92	2	315.6%	0.795	$3.10		$0.80	-0.199	258.5%	2	1.4k
Call · $5 In the money Last $3.10 Breakeven $8.10 Implied vol 315.6% Delta 0.795 ≈79% ITM Gamma 0.052 Theta -0.035 Vega 0.005 Open interest 92 Model this call Put · $5 Last $0.80 Breakeven $4.20 Implied vol 258.5% Delta -0.199 ≈20% ITM Gamma 0.062 Theta -0.028 Vega 0.005 Open interest 1.4k Model this put
Underlying $6.86
10.4k	5	357.7%	0.646	$2.00		$2.25	-0.356	354.6%	25	1.5k
Call · $7.5 Last $2.00 Breakeven $9.50 Implied vol 357.7% Delta 0.646 ≈65% ITM Gamma 0.059 Theta -0.052 Vega 0.006 Open interest 10.4k Model this call Put · $7.5 In the money Last $2.25 Breakeven $5.25 Implied vol 354.6% Delta -0.356 ≈36% ITM Gamma 0.06 Theta -0.051 Vega 0.006 Open interest 1.5k Model this put
3k	3	268.6%	0.426	$1.30		$4.50	-0.678	201.6%	55	250
Call · $10 Last $1.30 Breakeven $11.30 Implied vol 268.6% Delta 0.426 ≈43% ITM Gamma 0.083 Theta -0.041 Vega 0.007 Open interest 3k Model this call Put · $10 In the money Last $4.50 Breakeven $5.50 Implied vol 201.6% Delta -0.678 ≈68% ITM Gamma 0.103 Theta -0.027 Vega 0.007 Open interest 250 Model this put
1.9k	11	313%	0.36	$1.50		$3.80	-0.654	302.1%	22	22
Call · $12.5 Last $1.50 Breakeven $14.00 Implied vol 313% Delta 0.36 ≈36% ITM Gamma 0.069 Theta -0.046 Vega 0.006 Open interest 1.9k Model this call Put · $12.5 In the money Last $3.80 Breakeven $8.70 Implied vol 302.1% Delta -0.654 ≈65% ITM Gamma 0.07 Theta -0.042 Vega 0.006 Open interest 22 Model this put
5.3k	2	291.6%	0.247	$0.65		—	-0.688	333.8%	—	0
Call · $15 Last $0.65 Breakeven $15.65 Implied vol 291.6% Delta 0.247 ≈25% ITM Gamma 0.062 Theta -0.036 Vega 0.006 Open interest 5.3k Model this call Put · $15 In the money Last — Breakeven — Implied vol 333.8% Delta -0.688 ≈69% ITM Gamma 0.06 Theta -0.044 Vega 0.006 Open interest 0 Model this put
488	4	365.6%	0.294	$0.60		—	-0.823	285.5%	—	0
Call · $17.5 Last $0.60 Breakeven $18.10 Implied vol 365.6% Delta 0.294 ≈29% ITM Gamma 0.053 Theta -0.049 Vega 0.007 Open interest 488 Model this call Put · $17.5 In the money Last — Breakeven — Implied vol 285.5% Delta -0.823 ≈82% ITM Gamma 0.052 Theta -0.027 Vega 0.005 Open interest 0 Model this put
2.5k	2	388.6%	0.272	$0.25		—	-0.866	291.2%	—	0
Call · $20 Last $0.25 Breakeven $20.25 Implied vol 388.6% Delta 0.272 ≈27% ITM Gamma 0.049 Theta -0.05 Vega 0.007 Open interest 2.5k Model this call Put · $20 In the money Last — Breakeven — Implied vol 291.2% Delta -0.866 ≈87% ITM Gamma 0.044 Theta -0.023 Vega 0.005 Open interest 0 Model this put

About this data

Greeks, implied volatility, open interest and the last price come from the latest daily snapshot and are 15-minute delayed. Bid and ask are not included on this plan.

In-the-money strikes are tinted, deepening toward the money, and the bar beside each open-interest figure scales to the heaviest strike shown. Max pain is the listed strike where the most open interest would expire worthless — a positioning reference, not a forecast.

Key facts CIK 1503802 CUSIP 48576U205 13F (30d) 10 filings 10 filers Visit website Investor relations