JANE STREET GROUP, LLC

Position in KRYS — Krystal Biotech, Inc.

CIK 1595888 NEW YORK, NY

Back to KRYS Full portfolio

Position in KRYS

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$355,316

+$355,316 QoQ

Shares Held

956

Ownership

0.003%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#274

of 422 holders

Holding Since

Jun 2020

20 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in KRYS Over Time

Shares Held

Position Value (USD)

Derivatives in KRYS

reported options exposure · as of Jun 30, 2026

CallValue

$9,031,581

CallShares

24,300

PutValue

$1,189,344

PutShares

3,200

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,364,050,815 across 292 Biotechnology names. KRYS ranks #136 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	2,934,193	$218,538,693
2	MDGL	Madrigal Pharmaceuticals, Inc.	191,541	$102,847,939
3	AXSM	Axsome Therapeutics, Inc.	403,995	$98,885,855
4	TGTX	Tg Therapeutics, Inc.	1,752,646	$96,290,370
5	EXEL	Exelixis, Inc.	1,402,438	$76,306,651
6	QURE	uniQure N.V.	1,610,483	$74,178,846
7	HALO	Halozyme Therapeutics, Inc.	694,684	$54,372,915
8	TVTX	Travere Therapeutics, Inc.	938,699	$53,327,489

All Filings in KRYS

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37 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$1,189,344	3,200	-56.2%	Put	Defined	2026-08-14
2026-06-30	$355,316	956	-71.7%	Shares	Defined	2026-08-14
2026-06-30	$9,031,581	24,300	+31.4%	Call	Defined	2026-08-14
2026-03-31	$1,885,736	7,300	-69.3%	Put	Defined	2026-05-12
2026-03-31	$4,778,920	18,500	-39.1%	Call	Defined	2026-05-12
2025-12-31	$5,867,652	23,800	-57.3%	Put	Defined	2026-02-12
2025-12-31	$7,494,816	30,400	+300.0%	Call	Defined	2026-02-12
2025-09-30	$9,850,374	55,800	+3.7%	Put	Defined	2025-11-14
2025-09-30	$1,341,628	7,600	-88.4%	Call	Defined	2025-11-14
2025-09-30	$596,846	3,381	-85.7%	Shares	Defined	2025-11-14
2025-06-30	$7,395,348	53,800	+976.0%	Put	Defined	2025-08-14
2025-06-30	$9,003,630	65,500	+1293.6%	Call	Defined	2025-08-14
2025-03-31	$901,500	5,000	+56.2%	Put	Defined	2025-05-19
2025-03-31	$4,266,438	23,663	-34.0%	Shares	Defined	2025-05-19
2025-03-31	$847,410	4,700	-82.1%	Call	Defined	2025-05-19
2024-12-31	$501,312	3,200	-94.1%	Put	Defined	2025-02-14
2024-12-31	$5,617,044	35,855	+97.2%	Shares	Defined	2025-02-14
2024-12-31	$4,120,158	26,300	-33.4%	Call	Defined	2025-02-14
2024-09-30	$3,309,486	18,181	-76.6%	Shares	Defined	2024-11-15
2024-09-30	$7,190,185	39,500	+145.3%	Call	Defined	2024-11-15
2024-09-30	$9,957,041	54,700	+932.1%	Put	Defined	2024-11-15
2024-06-30	$14,293,068	77,832	-17.0%	Shares	Defined	2024-08-15
2024-03-31	$16,680,047	93,745	+85.2%	Shares	Defined	2024-05-16
2023-12-31	$6,279,667	50,618	-32.6%	Shares	Defined	2024-02-15
2023-09-30	$8,714,616	75,126	+340.5%	Shares	Defined	2023-11-15
2023-06-30	$2,002,256	17,055	-29.2%	Shares	Defined	2023-08-14
2023-03-31	$1,929,926	24,106	+434.6%	Shares	Defined	2023-05-16
2022-06-30	$296,060	4,509	-77.8%	Shares	Defined	2022-08-16
2022-03-31	$1,071,294	16,100	+27.8%	Call	Defined	2022-05-17
2022-03-31	$1,352,558	20,327	-26.6%	Shares	Defined	2022-05-17
2022-03-31	$352,662	5,300	-91.1%	Put	Defined	2022-05-17
2021-12-31	$1,936,494	27,684	+166.0%	Shares	Defined	2022-02-15
2021-12-31	$881,370	12,600	-63.4%	Call	Defined	2022-02-15
2021-12-31	$4,169,020	59,600	—	Put	Defined	2022-02-15
2021-09-30	$1,796,024	34,400	+247.5%	Call	Defined	2021-11-16
2020-12-31	$624,360	10,406	—	Shares	Defined	2021-02-17
2020-06-30	$410,058	9,900	—	Call	Defined	2020-08-17
No filing history on record for this holder in this stock.