Opaleye Management Inc.

CIK
1595855
City
Boston
State / Country
MA

Top Portfolio Positions

53 positions · $743,833,828 total · as of Mar 31, 2026
Ticker Company Shares Value (USD) % of Portfolio
HROW
Harrow, Inc.
Healthcare
2,832,230 $99,864,429 13.43%
LQDA
Liquidia Corp
Healthcare
2,545,000 $96,048,300 12.91%
ETON
Eton Pharmaceuticals, Inc.
Healthcare
2,860,000 $70,584,800 9.49%
SLGL
Sol-Gel Technologies Ltd.
Healthcare
500,000 $39,610,000 5.33%
APGE
Apogee Therapeutics, Inc.
Healthcare
390,000 $32,826,300 4.41%
IRON
Disc Medicine, Inc.
Healthcare
421,000 $26,918,740 3.62%
URGN
UroGen Pharma Ltd.
Healthcare
1,430,000 $25,711,400 3.46%
CBIO
Crescent Biopharma, Inc.
Healthcare
1,312,615 $24,112,737 3.24%
STOK
Stoke Therapeutics, Inc.
Healthcare
700,000 $22,792,000 3.06%
CATX
Perspective Therapeutics, Inc.
Healthcare
4,675,000 $19,494,750 2.62%

Portfolio Trend

25 quarters · across all stocks

Holdings in OCUL

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Shares Held

Position Value (USD)

25 of 25 shown
Report Date Value (USD) Shares
2026-03-31 $5,082,000 600,000
2025-12-31 $19,363,300 1,595,000
2025-09-30 $18,645,550 1,595,000
2025-06-30 $14,801,600 1,595,000
2025-03-31 $11,691,350 1,595,000
2024-12-31 $37,084,950 4,342,500
2024-09-30 $43,717,500 5,025,000
2024-06-30 $36,303,300 5,307,500
2024-03-31 $60,543,555 6,653,138
2023-12-31 $27,072,200 6,070,000
2023-09-30 $20,309,520 6,468,000
2023-06-30 $29,824,800 5,780,000
2023-03-31 $32,178,093 6,105,900
2022-12-31 $17,070,750 6,075,000
2022-09-30 $26,829,750 6,465,000
2022-06-30 $24,018,696 5,974,800
2022-03-31 $29,575,260 5,974,800
2021-12-31 $41,644,356 5,974,800
2021-09-30 $64,800,000 6,480,000
2021-06-30 $91,886,400 6,480,000
2021-03-31 $106,336,800 6,480,000
2020-12-31 $134,757,000 6,510,000
2020-09-30 $45,539,762 5,984,200
2020-06-30 $49,848,386 5,984,200
2020-03-31 $25,356,375 5,122,500