BARCLAYS PLC

CIK

312069

City

LONDON

State / Country

X0

Stock

PRME — Prime Medicine, Inc.

Top Portfolio Positions

3,769 positions · $331,702,477,339 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
MSFT	Microsoft Corp Technology	90,718,129	$33,581,129,808	10.12%
SPY	Spdr S&P 500 ETF Trust	50,435,151	$32,799,996,100	9.89%
NVDA	Nvidia Corp Technology	98,209,762	$17,127,782,490	5.16%
QQQ	Invesco Qqq Trust, Series 1	28,825,875	$16,637,718,531	5.02%
AAPL	Apple Inc. Technology	41,584,066	$10,553,620,108	3.18%
AMZN	Amazon Com Inc Consumer Cyclical	41,965,369	$8,740,127,398	2.63%
GOOGL	Alphabet Inc. Communication Services	27,728,578	$7,973,629,887	2.40%
META	Meta Platforms, Inc. Communication Services	12,417,494	$7,104,420,839	2.14%
AVGO	Broadcom Inc. Technology	20,117,836	$6,226,671,417	1.88%
TSLA	Tesla, Inc. Consumer Cyclical	13,762,733	$5,116,295,991	1.54%

Portfolio Trend

25 quarters · across all stocks

Holdings in PRME

Compact Export CSV

Shares Held

Position Value (USD)

14 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$221,929	63,773	-82.5%	Shares	Defined	2026-05-15
2025-12-31	$1,262,476	363,826	+213.9%	Shares	Sole	2026-02-13
2025-09-30	$642,086	115,900	+1.0%	Shares	Sole	2026-03-31
2025-06-30	$283,560	114,802	+60.7%	Shares	Sole	2026-02-27
2025-03-31	$142,133	71,424	-26.8%	Shares	Sole	2026-03-17
2024-12-31	$285,053	97,621	+15.3%	Shares	Sole	2026-03-19
2024-09-30	$327,777	84,697	+343.3%	Shares	Sole	2026-03-31
2024-06-30	$98,194	19,104	-30.8%	Shares	Sole	2026-03-23
2024-03-31	$193,130	27,590	-49.1%	Shares	Sole	2026-03-24
2023-12-31	$480,522	54,235	-16.7%	Shares	Sole	2026-03-24
2023-09-30	$621,435	65,140	+726.8%	Shares	Sole	2026-03-26
2023-06-30	$115,427	7,879	+47.7%	Shares	Sole	2026-03-27
2023-03-31	$65,632	5,336	+91.5%	Shares	Sole	2026-03-30
2022-12-31	$51,782	2,787	—	Shares	Sole	2026-03-30
No 13F history on record for this holder in this stock.