RENAISSANCE TECHNOLOGIES LLC

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1037389 NEW YORK, NY

Position in RYTM

as of Mar 31, 2026 · filed May 14, 2026 Compact

Position Value

$22,439,216

-$14,082,082 QoQ

Shares Held

258,011

-24.4% QoQ

Ownership

0.376%

of shares outstanding

% of Portfolio

0.04%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

12 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

RENAISSANCE TECHNOLOGIES LLC holds $3,447,997,584 across 326 Biotechnology names. RYTM ranks #33 (0.7% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	EXEL	Exelixis, Inc.	13,726,993	$588,750,729
2	INCY	Incyte Corp	3,651,532	$343,682,191
3	CORT	Corcept Therapeutics Inc	5,682,783	$229,072,982
4	VRTX	Vertex Pharmaceuticals Inc / Ma	421,688	$188,300,559
5	JAZZ	Jazz Pharmaceuticals plc	819,374	$154,902,654
6	GMAB	Genmab A/S	4,414,550	$118,442,376
7	INVA	Innoviva, Inc.	4,055,632	$94,496,225
8	ARWR	Arrowhead Pharmaceuticals, Inc.	1,036,495	$64,988,236

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$22,439,216	258,011	-24.4%	Shares	Sole	2026-05-14
2025-12-31	$36,521,298	341,193	-37.6%	Shares	Sole	2026-02-12
2025-09-30	$55,200,427	546,593	+73.6%	Shares	Sole	2025-11-13
2025-06-30	$19,898,088	314,893	+2131.4%	Shares	Sole	2025-08-13
2025-03-31	$747,512	14,112	-38.9%	Shares	Sole	2025-05-14
2022-03-31	$266,112	23,100	-55.7%	Shares	Sole	2022-05-13
2021-06-30	$1,022,076	52,200	+6.5%	Shares	Sole	2021-08-13
2021-03-31	$1,042,230	49,000	+390.0%	Shares	Sole	2021-05-13
2020-12-31	$297,300	10,000	-94.9%	Shares	Sole	2021-02-10
2020-09-30	$4,268,990	197,000	-16.5%	Shares	Sole	2020-11-13
2020-06-30	$5,260,570	235,900	+149.1%	Shares	Sole	2020-08-13
2020-03-31	$1,441,334	94,700	—	Shares	Sole	2020-05-14
No filing history on record for this holder in this stock.