BAKER BROS. ADVISORS LP

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1263508 NEW YORK, NY

Position in RYTM

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$487,421,886

-$112,481,974 QoQ

Shares Held

5,604,483

0.0% QoQ

Ownership

8.18%

of shares outstanding

% of Portfolio

2.81%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

BAKER BROS. ADVISORS LP holds $16,600,149,582 across 76 Biotechnology names. RYTM ranks #12 (2.9% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	INCY	Incyte Corp	30,744,412	$2,893,664,057
2	ONC	BeOne Medicines Ltd.	8,799,053	$2,613,054,769
3	INSM	INSMED Inc	7,421,111	$1,213,500,070
4	MDGL	Madrigal Pharmaceuticals, Inc.	2,141,701	$1,121,116,222
5	ACAD	Acadia Pharmaceuticals Inc	42,896,690	$954,880,319
6	RVMD	Revolution Medicines, Inc.	9,555,357	$929,258,468
7	CELC	Celcuity Inc.	7,915,792	$903,508,498
8	KOD	Kodiak Sciences Inc.	19,919,186	$759,319,370

25 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$487,421,886	5,604,483	0.0%	Shares	Sole	2026-05-15
2025-12-31	$599,903,860	5,604,483	0.0%	Shares	Sole	2026-02-17
2025-09-30	$565,996,738	5,604,483	0.0%	Shares	Sole	2025-11-14
2025-06-30	$354,147,280	5,604,483	0.0%	Shares	Sole	2025-08-14
2025-03-31	$296,869,464	5,604,483	-7.9%	Shares	Sole	2025-05-15
2024-12-31	$340,596,259	6,084,249	-4.9%	Shares	Sole	2025-02-14
2024-09-30	$335,210,394	6,398,366	+0.0%	Shares	Sole	2024-11-14
2024-06-30	$262,716,866	6,398,365	0.0%	Shares	Sole	2024-08-14
2024-03-31	$277,241,155	6,398,365	0.0%	Shares	Sole	2024-05-15
2023-12-31	$294,132,839	6,398,365	-4.5%	Shares	Sole	2024-02-14
2023-09-30	$153,651,350	6,702,349	+3.1%	Shares	Sole	2023-11-14
2023-06-30	$107,156,422	6,498,267	0.0%	Shares	Sole	2023-08-14
2023-03-31	$115,929,083	6,498,267	+2.3%	Shares	Sole	2023-05-15
2022-12-31	$185,046,184	6,354,608	+4.8%	Shares	Sole	2023-02-14
2022-09-30	$148,536,199	6,062,702	+47.0%	Shares	Sole	2022-11-14
2022-06-30	$17,119,007	4,125,062	0.0%	Shares	Sole	2022-08-15
2022-03-31	$47,520,714	4,125,062	+6.8%	Shares	Sole	2022-05-16
2021-12-31	$38,555,125	3,863,239	0.0%	Shares	Sole	2022-02-14
2021-09-30	$50,453,901	3,863,239	0.0%	Shares	Sole	2021-11-15
2021-06-30	$75,642,219	3,863,239	+11.0%	Shares	Sole	2021-08-16
2021-03-31	$74,016,898	3,479,873	+50.3%	Shares	Sole	2021-05-17
2020-12-31	$68,821,174	2,314,873	-6.3%	Shares	Sole	2021-02-16
2020-09-30	$53,549,928	2,471,155	-8.5%	Shares	Sole	2020-11-16
2020-06-30	$60,211,226	2,700,055	-0.3%	Shares	Sole	2020-08-14
2020-03-31	$41,218,804	2,708,200	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.