Clearbridge Investments, LLC

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1348883 NEW YORK, NY

Position in RYTM

as of Jun 30, 2026 · filed Aug 13, 2026 Compact

Position Value

$77,329,397

+$24,326,662 QoQ

Shares Held

696,473

+14.3% QoQ

Ownership

1.01%

of shares outstanding

% of Portfolio

0.06%

of 13F equity value

Holder Rank

#26

of 299 holders

Holding Since

Mar 2020

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

Clearbridge Investments, LLC holds $2,924,434,154 across 28 Biotechnology names. RYTM ranks #6 (2.6% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	2,342,915	$1,163,796,167
2	ALNY	Alnylam Pharmaceuticals, Inc.	1,259,483	$379,142,167
3	ARGX	Argenx SE	253,776	$235,445,759
4	TGTX	Tg Therapeutics, Inc.	2,650,192	$145,601,548
5	PTGX	Protagonist Therapeutics, Inc	725,335	$88,911,564
6	RYTM	Rhythm Pharmaceuticals, Inc. This page	696,473	$77,329,397
7	INSM	INSMED Inc	715,922	$76,331,603
8	MIRM	Mirum Pharmaceuticals, Inc.	639,734	$74,893,659

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$77,329,397	696,473	+14.3%	Shares	Sole	2026-08-13
2026-03-31	$53,002,735	609,437	+20.4%	Shares	Sole	2026-05-13
2025-12-31	$54,173,907	506,109	+4.4%	Shares	Sole	2026-02-11
2025-09-30	$48,953,084	484,732	+55.1%	Shares	Sole	2025-11-13
2025-06-30	$19,743,399	312,445	+257.4%	Shares	Sole	2025-08-12
2024-09-30	$4,580,143	87,424	-0.8%	Shares	Sole	2024-11-12
2024-06-30	$3,617,714	88,108	-2.1%	Shares	Sole	2024-08-27
2024-03-31	$3,899,873	90,004	-1.3%	Shares	Sole	2024-05-13
2023-12-31	$4,190,533	91,158	-50.1%	Shares	Sole	2024-02-09
2023-09-30	$4,191,263	182,825	+25152.1%	Shares	Sole	2023-11-13
2020-06-30	$16,145	724	0.0%	Shares	Defined	2020-08-14
2020-03-31	$11,019	724	—	Shares	Defined	2020-05-22
No filing history on record for this holder in this stock.