Clearbridge Investments, LLC

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1348883 NEW YORK, NY

Position in RYTM

as of Mar 31, 2026 · filed May 13, 2026 Compact

Position Value

$53,002,735

-$1,171,172 QoQ

Shares Held

609,437

+20.4% QoQ

Ownership

0.889%

of shares outstanding

% of Portfolio

0.05%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

11 quarters on record

Voting authority Sole 99.99360065109273.ToString("F0")% Shared 0.ToString("F0")% None 0.006399348907270152.ToString("F0")%

Healthcare · as of Mar 31, 2026

Clearbridge Investments, LLC holds $2,718,012,251 across 26 Biotechnology names. RYTM ranks #12 (2.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	2,700,975	$1,206,093,376
2	ALNY	Alnylam Pharmaceuticals, Inc.	1,356,036	$448,671,631
3	ARGX	Argenx SE	231,356	$168,947,719
4	TGTX	Tg Therapeutics, Inc.	3,210,930	$106,667,094
5	INSM	INSMED Inc	643,435	$105,214,491
6	BBIO	BridgeBio Pharma, Inc.	951,200	$70,636,112
7	PTGX	Protagonist Therapeutics, Inc	621,820	$65,539,828
8	MIRM	Mirum Pharmaceuticals, Inc.	671,870	$62,067,350

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$53,002,735	609,437	+20.4%	Shares	Sole	2026-05-13
2025-12-31	$54,173,907	506,109	+4.4%	Shares	Sole	2026-02-11
2025-09-30	$48,953,084	484,732	+55.1%	Shares	Sole	2025-11-13
2025-06-30	$19,743,399	312,445	+257.4%	Shares	Sole	2025-08-12
2024-09-30	$4,580,143	87,424	-0.8%	Shares	Sole	2024-11-12
2024-06-30	$3,617,714	88,108	-2.1%	Shares	Sole	2024-08-27
2024-03-31	$3,899,873	90,004	-1.3%	Shares	Sole	2024-05-13
2023-12-31	$4,190,533	91,158	-50.1%	Shares	Sole	2024-02-09
2023-09-30	$4,191,263	182,825	+25152.1%	Shares	Sole	2023-11-13
2020-06-30	$16,145	724	0.0%	Shares	Defined	2020-08-14
2020-03-31	$11,019	724	—	Shares	Defined	2020-05-22
No filing history on record for this holder in this stock.