SPHERA FUNDS MANAGEMENT LTD.

Position in SKYE — Skye Bioscience, Inc.

CIK 1496201 TEL AVIV, L3

Position in SKYE

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$417,540

+$58,344 QoQ

Shares Held

678,928

+41.8% QoQ

Ownership

1.93%

of shares outstanding

% of Portfolio

0.07%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Jun 2024

8 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Mar 31, 2026

SPHERA FUNDS MANAGEMENT LTD. holds $324,179,213 across 61 Biotechnology names. SKYE ranks #57 (0.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	MLYS	Mineralys Therapeutics, Inc.	1,339,971	$36,299,814
2	BBIO	BridgeBio Pharma, Inc.	245,246	$18,211,967
3	RARE	Ultragenyx Pharmaceutical Inc.	809,333	$16,955,526
4	SNDX	Syndax Pharmaceuticals Inc	724,563	$16,925,791
5	COGT	Cogent Biosciences, Inc.	416,340	$16,024,926
6	FOLD	AMICUS THERAPEUTICS, INC.	603,377	$8,724,831
7	APLS	Apellis Pharmaceuticals, Inc.	214,914	$8,645,990
8	BMRN	Biomarin Pharmaceutical Inc	139,900	$7,902,951

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$417,540	678,928	+41.8%	Shares	Defined	2026-05-15
2025-12-31	$359,196	478,928	0.0%	Shares	Defined	2026-02-17
2025-09-30	$1,882,187	478,928	-11.1%	Shares	Defined	2025-11-14
2025-06-30	$2,250,654	538,434	-63.5%	Shares	Defined	2025-08-14
2025-03-31	$2,347,401	1,476,353	0.0%	Shares	Sole	2025-04-10
2025-03-31	$2,347,401	1,476,353	-5.6%	Shares	Defined	2025-05-15
2024-12-31	$4,427,897	1,564,628	+0.1%	Shares	Defined	2025-02-14
2024-09-30	$6,113,371	1,563,522	+20.4%	Shares	Defined	2024-11-14
2024-06-30	$10,399,479	1,298,312	—	Shares	Defined	2024-08-14
No filing history on record for this holder in this stock.