CHARLES SCHWAB INVESTMENT MANAGEMENT INC
Position in SPRB — Spruce Biosciences, Inc.
CIK 884546
SAN FRANCISCO, CA
Position in SPRB
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$318,384
+$310,465 QoQ
Shares Held
5,896
+196433.3% QoQ
Ownership
0.205%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#36
of 63 holders
Holding Since
Dec 2020
12 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in SPRB Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026CHARLES SCHWAB INVESTMENT MANAGEMENT INC holds $7,402,603,842 across 299 Biotechnology names. SPRB ranks #274 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
2,041,282 | $1,013,966,007 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
846,306 | $527,705,642 | |
| 3 | RVMD |
Revolution Medicines, Inc.
|
1,917,025 | $359,020,441 | |
| 4 | MRNA |
Moderna, Inc.
|
4,838,884 | $338,867,045 | |
| 5 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
755,377 | $227,391,137 | |
| 6 | INCY |
Incyte Corp
|
1,692,439 | $191,854,884 | |
| 7 | RPRX |
Royalty Pharma plc
|
3,083,528 | $172,893,414 | |
| 8 | CYTK |
Cytokinetics Inc
|
1,565,781 | $133,388,883 |
All Filings in SPRB
Export CSV
12 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $318,384 | 5,896 | Shares | Sole | 2026-08-14 | |
| 2024-06-30 | $7,919 | 15,289 | Shares | Sole | 2024-08-12 | |
| 2024-03-31 | $12,017 | 15,289 | Shares | Sole | 2024-05-09 | |
| 2023-12-31 | $44,796 | 15,289 | Shares | Sole | 2024-02-06 | |
| 2023-09-30 | $34,553 | 15,289 | Shares | Sole | 2023-11-08 | |
| 2023-06-30 | $32,871 | 15,289 | Shares | Sole | 2023-08-10 | |
| 2022-03-31 | $37,018 | 18,417 | Shares | Sole | 2022-05-13 | |
| 2021-12-31 | $82,139 | 18,417 | Shares | Sole | 2022-02-11 | |
| 2021-09-30 | $110,686 | 18,417 | Shares | Sole | 2021-11-16 | |
| 2021-06-30 | $484,597 | 43,229 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $732,690 | 44,138 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $980,957 | 40,352 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||