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Equibles

JANE STREET GROUP, LLC

Position in SPRO — Spero Therapeutics, Inc.

CIK 1595888 NEW YORK, NY
Back to SPRO Full portfolio

Position in SPRO

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$349,394
+$100,548 QoQ
Shares Held
158,097
+48.7% QoQ
Ownership
0.271%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#17
of 59 holders
Holding Since
Mar 2021
8 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SPRO Over Time

Shares Held

Position Value (USD)

Derivatives in SPRO

reported options exposure · as of Jun 30, 2026
CallValue
$104,091
CallShares
47,100
PutValue
$59,228
PutShares
26,800

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,372,940,661 across 293 Biotechnology names. SPRO ranks #139 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 BBIO
BridgeBio Pharma, Inc.
 2,934,193 $218,538,693
2 MDGL
Madrigal Pharmaceuticals, Inc.
 191,541 $102,847,939
3 AXSM
Axsome Therapeutics, Inc.
 403,995 $98,885,855
4 TGTX
Tg Therapeutics, Inc.
 1,752,646 $96,290,370
5 EXEL
Exelixis, Inc.
 1,402,438 $76,306,651
6 QURE
uniQure N.V.
 1,610,483 $74,178,846
7 HALO
Halozyme Therapeutics, Inc.
 694,684 $54,372,915
8 TVTX
Travere Therapeutics, Inc.
 938,699 $53,327,489

All Filings in SPRO

Export CSV
13 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $104,091 47,100
2026-06-30 $59,228 26,800
2026-06-30 $349,394 158,097
2026-03-31 $248,846 106,345
2026-03-31 $90,090 38,500
2026-03-31 $88,452 37,800
2025-12-31 $89,938 38,600
2025-12-31 $368,941 158,344
2025-09-30 $80,816 42,988
2024-12-31 $54,455 52,869
2022-09-30 $30,992 15,496
2022-03-31 $135,911 15,622
2021-03-31 $169,221 11,496