Opaleye Management Inc.

Position in TRVI — Trevi Therapeutics, Inc.

CIK 1595855 Boston, MA

Position in TRVI

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$5,781,500

+$1,664,457 QoQ

Shares Held

310,000

-10.2% QoQ

Ownership

0.218%

of shares outstanding

% of Portfolio

0.53%

of 13F equity value

Holder Rank

#59

of 216 holders

Holding Since

Dec 2022

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

Opaleye Management Inc. holds $677,784,861 across 50 Biotechnology names. TRVI ranks #29 (0.9% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	IRON	Disc Medicine, Inc.	855,000	$62,534,700
2	URGN	UroGen Pharma Ltd.	1,439,996	$52,991,852
3	APGE	Apogee Therapeutics, Inc.	390,000	$51,764,700
4	MGTX	MeiraGTx Holdings plc	3,550,000	$47,960,500
5	SLGL	Sol-Gel Technologies Ltd.	500,000	$37,070,000
6	RZLT	Rezolute, Inc.	6,300,000	$32,760,000
7	TGTX	Tg Therapeutics, Inc.	535,000	$29,392,900
8	IMMX	Immix Biopharma, Inc.	2,345,000	$24,176,950

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$5,781,500	310,000	-10.2%	Shares	Sole	2026-08-14
2026-03-31	$4,117,043	345,100	-11.5%	Shares	Sole	2026-05-15
2025-09-30	$3,568,500	390,000	-50.9%	Shares	Sole	2025-11-14
2025-03-31	$5,000,550	795,000	-65.7%	Shares	Sole	2025-05-15
2024-12-31	$9,548,100	2,317,500	-9.8%	Shares	Sole	2025-02-14
2024-09-30	$8,577,086	2,567,990	-2.9%	Shares	Sole	2024-11-14
2024-06-30	$7,882,100	2,645,000	+4.3%	Shares	Sole	2024-08-14
2023-12-31	$3,396,900	2,535,000	+48.6%	Shares	Sole	2024-02-14
2023-09-30	$3,718,862	1,705,900	+0.3%	Shares	Sole	2023-11-15
2023-06-30	$4,066,585	1,701,500	+103.6%	Shares	Sole	2023-08-14
2023-03-31	$1,546,230	835,800	+72.3%	Shares	Sole	2023-05-15
2022-12-31	$936,050	485,000	—	Shares	Sole	2023-02-10
No filing history on record for this holder in this stock.