Sio Capital Management, LLC

CIK

1482416

City

NEW YORK

State / Country

NY

Stock

TYRA — Tyra Biosciences, Inc.

Top Portfolio Positions

72 positions · $729,621,343 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
AVR	Anteris Technologies Global Corp. Healthcare	10,765,930	$59,750,910	8.19%
MMS	Maximus, Inc. Industrials	768,825	$49,281,682	6.75%
WAY	Waystar Holding Corp. Healthcare	1,642,236	$39,594,309	5.43%
ICLR	Icon PLC Healthcare	306,358	$33,901,576	4.65%
COR	Cencora, Inc. Healthcare	100,894	$31,694,841	4.34%
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	370,045	$31,054,176	4.26%
CORT	Corcept Therapeutics Inc Healthcare	674,759	$27,199,535	3.73%
LIVN	LivaNova PLC Healthcare	421,615	$26,797,849	3.67%
TYRA	Tyra Biosciences, Inc. Healthcare	605,439	$23,188,313	3.18%
CELC	Celcuity Inc. Healthcare	193,843	$22,125,240	3.03%

Portfolio Trend

25 quarters · across all stocks

Holdings in TYRA

Compact Export CSV

Shares Held

Position Value (USD)

13 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$23,188,313	605,439	+15.1%	Shares	Sole	2026-05-14
2025-12-31	$13,828,592	526,002	+2.1%	Shares	Sole	2026-02-17
2025-09-30	$7,204,108	514,947	-36.4%	Shares	Sole	2025-11-13
2025-06-30	$7,754,322	810,274	+94.5%	Shares	Sole	2025-08-13
2025-03-31	$3,874,538	416,617	+73.0%	Shares	Sole	2025-05-15
2024-12-31	$3,348,093	240,870	-39.9%	Shares	Sole	2025-02-14
2024-09-30	$9,424,453	400,870	-33.2%	Shares	Sole	2024-11-14
2024-06-30	$9,598,701	600,294	+12.0%	Shares	Sole	2024-08-14
2024-03-31	$8,786,152	535,741	+252.1%	Shares	Sole	2024-05-15
2022-12-31	$1,156,408	152,159	0.0%	Shares	Sole	2023-02-13
2022-09-30	$1,337,477	152,159	0.0%	Shares	Sole	2022-11-14
2022-06-30	$1,087,936	152,159	+37.0%	Shares	Sole	2022-08-15
2022-03-31	$1,188,053	111,033	—	Shares	Sole	2022-05-16
No 13F history on record for this holder in this stock.