Sio Capital Management, LLC

CIK

1482416

Location

NEW YORK, NY

Portfolio Value

Small $589,783,077

Diversification

Diversified

Filing Date

Global Rank

#2,604 / 8,700 ▲ 306

Top Industry

Biotechnology 41.2%

Period ended 2 months ago

Filed Aug 14, 2026 · 30d

26 quarters · since Mar 2020

Portfolio Concentration

59 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

9.3%

+2.1 pts

Top 5

32.9%

+5.8 pts

Top 10

49.8%

+4.0 pts

HHI

382

Diversified+74

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	93.5%	$551,330,324	58
Industrials	6.5%	$38,452,753	1

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

10 positions

Ticker	Company	Δ Shares	Shares	Value
SENS	Senseonics Holdings, Inc.	+1,476,908	1,592,692	$9,046,490
AVR	Anteris Technologies Global Corp.	+163,019	5,545,984	$54,627,942
SNY	Sanofi	+124,529	364,200	$15,536,772
TYRA	Tyra Biosciences, Inc.	+89,876	695,315	$22,208,361
COR	Cencora, Inc.	+72,694	173,588	$49,121,932
ZBH	Zimmer Biomet Holdings, Inc.	+68,832	131,445	$11,316,100
GSK	GSK plc	+50,821	436,700	$22,891,814
ORKA	Oruka Therapeutics, Inc.	+44,622	177,118	$16,856,320
RLMD	Relmada Therapeutics, Inc.	+38,562	1,003,562	$6,944,649
SVRA	Savara Inc	+3,787	617,675	$3,804,878
No positions match the current search.

Trimmed

Positions the filer reduced

22 positions

Ticker	Company	Δ Shares	Shares	Value
WAY	Waystar Holding Corp.	−716,402	925,834	$19,007,372
ADGM	Adagio Medical Holdings, Inc.	−589,472	698,989	$455,740
PMVP	PMV Pharmaceuticals, Inc.	−442,443	2,634,137	$3,529,743
AQST	Aquestive Therapeutics, Inc.	−436,712	1,486,175	$6,182,488
OCUL	Ocular Therapeutix, Inc	−429,104	539,493	$5,297,821
VIR	Vir Biotechnology, Inc.	−423,346	1,075,274	$10,957,042
NMTC	NEUROONE MEDICAL TECHNOLOGIES Corp	−413,847	82,767	$251,611
DNTH	Dianthus Therapeutics, Inc. /DE/	−310,791	59,254	$5,776,079
OVID	Ovid Therapeutics Inc.	−247,047	1,005,334	$2,704,348
ICLR	Icon PLC	−218,172	88,186	$15,318,790
ANIP	Ani Pharmaceuticals Inc	−168,238	97,305	$8,054,907
SION	Sionna Therapeutics, Inc.	−166,532	127,808	$5,622,273
ANTX	AN2 Therapeutics, Inc.	−127,267	529,933	$2,564,875
ZBIO	Zenas BioPharma, Inc.	−123,173	208,557	$5,293,176
EYPT	EyePoint, Inc.	−98,655	623,130	$8,910,759
CELC	Celcuity Inc.	−83,821	110,022	$11,510,501
RAPP	Rapport Therapeutics, Inc.	−59,152	307,657	$12,820,067
ABT	Abbott Laboratories	−57,918	128,656	$11,674,245
MMS	Maximus, Inc.	−53,558	715,267	$38,452,753
TARA	Protara Therapeutics, Inc.	−47,967	1,921,872	$7,341,551
IMNM	Immunome Inc.	−40,942	124,168	$2,631,119
DRUG	Bright Minds Biosciences Inc.	−12,131	73,952	$5,191,430
No positions match the current search.

New Positions

Positions the filer opened this quarter

17 positions

Ticker	Company	Shares	Value
ALLO	Allogene Therapeutics, Inc.	13,323,431	$27,712,736
GMED	Globus Medical Inc	301,816	$23,846,482
SLS	SELLAS Life Sciences Group, Inc.	1,230,700	$18,165,132
IDYA	IDEAYA Biosciences, Inc.	480,383	$17,903,874
CI	Cigna Group	57,750	$15,920,520
VTRS	Viatris Inc	954,299	$15,154,268
REGN	Regeneron Pharmaceuticals, Inc.	18,000	$11,223,720
BMY	Bristol Myers Squibb Co	193,500	$11,149,470
MDT	Medtronic plc	142,500	$11,147,775
HELP	Cybin Inc.	1,300,000	$8,593,000
TNGX	Tango Therapeutics, Inc.	208,500	$6,517,710
AVAH	Aveanna Healthcare Holdings, Inc.	369,036	$3,162,638
HIMS	Hims & Hers Health, Inc.	75,000	$2,600,250
AORT	Artivion, Inc.	48,481	$1,089,368
ENVB	Enveric Biosciences, Inc.	180,000	$248,400
QTI	Qt Imaging Holdings, Inc.	15,236	$62,010
RCKT	Rocket Pharmaceuticals, Inc.	400,000	$0
No positions match the current search.

Sold Out

Positions the filer fully exited

25 positions

Ticker	Company	Shares	Value
CORT	Corcept Therapeutics Inc	674,759	$27,199,535
LIVN	LivaNova PLC	421,615	$26,797,849
EMBC	Embecta Corp.	1,847,850	$16,334,994
ABVX	Abivax S.A.	135,800	$15,121,330
HAE	Haemonetics Corp	220,672	$12,437,073
TFX	Teleflex Inc	94,800	$11,339,028
BMRN	Biomarin Pharmaceutical Inc	194,226	$10,971,826
GPCR	Structure Therapeutics Inc.	209,093	$10,078,282
BHVN	Biohaven Ltd.	1,163,926	$9,846,813
MNPR	Monopar Therapeutics	173,506	$9,506,393
CRNX	Crinetics Pharmaceuticals, Inc.	249,887	$9,075,895
EWTX	Edgewise Therapeutics, Inc.	268,986	$8,473,059
CMPS	COMPASS Pathways plc	1,506,525	$8,331,083
QDEL	QuidelOrtho Corp	359,011	$5,898,550
REPL	Replimune Group, Inc.	720,036	$5,508,275
OGN	Organon & Co.	865,908	$5,186,788
IRON	Disc Medicine, Inc.	65,203	$4,169,079
IART	Integra Lifesciences Holdings Corp	383,140	$3,609,178
CNC	Centene Corp	100,000	$3,274,000
PRQR	ProQR Therapeutics N.V.	1,954,715	$3,166,638
SI	Shoulder Innovations, Inc.	210,641	$3,060,613
KYMR	Kymera Therapeutics, Inc.	32,235	$2,684,853
CNTX	Context Therapeutics Inc.	917,922	$2,404,955
HYPR	Hyperfine, Inc.	1,000,000	$1,080,000
FHTX	Foghorn Therapeutics Inc.	122,889	$587,409
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

59 tracked positions · $589,783,077 total · filing declares 59 positions · $604,294,540 · as of Jun 30, 2026

All sectors Healthcare Industrials

Showing 1–50 of 59 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
AVR	Anteris Technologies Global Corp. Healthcare	Added	5,545,984	+163,019	$54,627,942	+82.9%	9.26%
COR	Cencora, Inc. Healthcare	Added	173,588	+72,694	$49,121,932	+55.0%	8.33%
MMS	Maximus, Inc. Industrials	Reduced	715,267	-53,558	$38,452,753	−22.0%	6.52%
ALLO	Allogene Therapeutics, Inc. Healthcare	NEW	13,323,431	NEW	$27,712,736	NEW	4.70%
GMED	Globus Medical Inc Healthcare	NEW	301,816	NEW	$23,846,482	NEW	4.04%
GSK	GSK plc Healthcare	Added	436,700	+50,821	$22,891,814	+7.5%	3.88%
TYRA	Tyra Biosciences, Inc. Healthcare	Added	695,315	+89,876	$22,208,361	−4.2%	3.77%
WAY	Waystar Holding Corp. Healthcare	Reduced	925,834	-716,402	$19,007,372	−52.0%	3.22%
SLS	SELLAS Life Sciences Group, Inc. PUT Healthcare	NEW	1,230,700	NEW	$18,165,132	NEW	3.08%
IDYA	IDEAYA Biosciences, Inc. Healthcare	NEW	480,383	NEW	$17,903,874	NEW	3.04%
ORKA	Oruka Therapeutics, Inc. Healthcare	Added	177,118	+44,622	$16,856,320	+159.4%	2.86%
CI	Cigna Group Healthcare	NEW	57,750	NEW	$15,920,520	NEW	2.70%
SNY	Sanofi Healthcare	Added	364,200	+124,529	$15,536,772	+34.5%	2.63%
ICLR	Icon PLC Healthcare	Reduced	88,186	-218,172	$15,318,790	−54.8%	2.60%
VTRS	Viatris Inc Healthcare	NEW	954,299	NEW	$15,154,268	NEW	2.57%
RAPP	Rapport Therapeutics, Inc. Healthcare	Reduced	307,657	-59,152	$12,820,067	+11.7%	2.17%
ABT	Abbott Laboratories Healthcare	Reduced	128,656	-57,918	$11,674,245	−39.1%	1.98%
CELC	Celcuity Inc. Healthcare	Reduced	110,022	-83,821	$11,510,501	−48.0%	1.95%
ZBH	Zimmer Biomet Holdings, Inc. Healthcare	Added	131,445	+68,832	$11,316,100	+99.9%	1.92%
REGN	Regeneron Pharmaceuticals, Inc. Healthcare	NEW	18,000	NEW	$11,223,720	NEW	1.90%
BMY	Bristol Myers Squibb Co Healthcare	NEW	193,500	NEW	$11,149,470	NEW	1.89%
MDT	Medtronic plc Healthcare	NEW	142,500	NEW	$11,147,775	NEW	1.89%
VIR	Vir Biotechnology, Inc. Healthcare	Reduced	1,075,274	-423,346	$10,957,042	−18.4%	1.86%
SENS	Senseonics Holdings, Inc. Healthcare	Added	1,592,692	+1,476,908	$9,046,490	+1073.2%	1.53%
EYPT	EyePoint, Inc. Healthcare	Reduced	623,130	-98,655	$8,910,759	−4.2%	1.51%
HELP	Cybin Inc. Healthcare	NEW	1,300,000	NEW	$8,593,000	NEW	1.46%
ANIP	Ani Pharmaceuticals Inc Healthcare	Reduced	97,305	-168,238	$8,054,907	−60.6%	1.37%
TARA	Protara Therapeutics, Inc. Healthcare	Reduced	1,921,872	-47,967	$7,341,551	−28.5%	1.24%
RLMD	Relmada Therapeutics, Inc. Healthcare	Added	1,003,562	+38,562	$6,944,649	+3.4%	1.18%
TNGX	Tango Therapeutics, Inc. Healthcare	NEW	208,500	NEW	$6,517,710	NEW	1.11%
AQST	Aquestive Therapeutics, Inc. Healthcare	Reduced	1,486,175	-436,712	$6,182,488	−22.5%	1.05%
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	Reduced	59,254	-310,791	$5,776,079	−81.4%	0.98%
SION	Sionna Therapeutics, Inc. Healthcare	Reduced	127,808	-166,532	$5,622,273	−52.4%	0.95%
OCUL	Ocular Therapeutix, Inc Healthcare	Reduced	539,493	-429,104	$5,297,821	−35.4%	0.90%
ZBIO	Zenas BioPharma, Inc. Healthcare	Reduced	208,557	-123,173	$5,293,176	−18.4%	0.90%
DRUG	Bright Minds Biosciences Inc. Healthcare	Reduced	73,952	-12,131	$5,191,430	−17.4%	0.88%
OKUR	OnKure Therapeutics, Inc. Healthcare	Held	1,078,965	0	$4,920,080	+10.1%	0.83%
SVRA	Savara Inc Healthcare	Added	617,675	+3,787	$3,804,878	+13.5%	0.65%
PMVP	PMV Pharmaceuticals, Inc. Healthcare	Reduced	2,634,137	-442,443	$3,529,743	−7.5%	0.60%
AVAH	Aveanna Healthcare Holdings, Inc. Healthcare	NEW	369,036	NEW	$3,162,638	NEW	0.54%
OVID	Ovid Therapeutics Inc. Healthcare	Reduced	1,005,334	-247,047	$2,704,348	−2.7%	0.46%
IMNM	Immunome Inc. Healthcare	Reduced	124,168	-40,942	$2,631,119	−27.1%	0.45%
HIMS	Hims & Hers Health, Inc. CALL Healthcare	NEW	75,000	NEW	$2,600,250	NEW	0.44%
ANTX	AN2 Therapeutics, Inc. Healthcare	Reduced	529,933	-127,267	$2,564,875	+14.1%	0.43%
SER	Serina Therapeutics, Inc. Healthcare	Held	1,000,000	0	$1,940,000	0.0%	0.33%
ALGS	Aligos Therapeutics, Inc. Healthcare	Held	327,237	0	$1,888,157	−22.3%	0.32%
IBIO	iBio, Inc. Healthcare	Held	904,268	0	$1,582,469	−7.9%	0.27%
XLO	Xilio Therapeutics, Inc. Healthcare	Held	152,464	0	$1,460,605	+13.9%	0.25%
AORT	Artivion, Inc. Healthcare	NEW	48,481	NEW	$1,089,368	NEW	0.18%
BBOT	BridgeBio Oncology Therapeutics, Inc. Healthcare	Held	130,628	0	$995,385	−14.9%	0.17%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.