SIG BROKERAGE, LP
Broker-DealerPosition in VRTX — Vertex Pharmaceuticals Inc / Ma
CIK 1094429
BALA CYNWYD, PA
Position in VRTX
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$7,861,336
-$1,597,567 QoQ
Shares Held
17,605
-15.6% QoQ
Ownership
0.007%
of shares outstanding
% of Portfolio
3.30%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2024
6 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in VRTX Over Time
Shares Held
Position Value (USD)
Derivatives in VRTX
reported options exposure · as of Dec 31, 2025CallValue
$906,720
CallShares
2,000
PutValue
$4,306,920
PutShares
9,500
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026SIG BROKERAGE, LP holds $10,788,089 across 9 Biotechnology names. VRTX ranks #1 (72.9% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
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|
17,605 | $7,861,336 | |
| 2 | DNTH |
Dianthus Therapeutics, Inc. /DE/
|
20,292 | $1,702,904 | |
| 3 | CYTK |
Cytokinetics Inc
|
6,011 | $396,185 | |
| 4 | AXSM |
Axsome Therapeutics, Inc.
|
2,298 | $388,407 | |
| 5 | CRSP |
CRISPR Therapeutics AG
|
4,326 | $205,787 | |
| 6 | CMPX |
Compass Therapeutics, Inc.
|
14,496 | $76,683 | |
| 7 | SLS |
SELLAS Life Sciences Group, Inc.
|
15,429 | $65,264 | |
| 8 | NMRA |
Neumora Therapeutics, Inc.
|
27,483 | $53,591 |
All Filings in VRTX
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14 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $7,861,336 | 17,605 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $906,720 | 2,000 | Call | Sole | 2026-02-17 | |
| 2025-12-31 | $9,458,903 | 20,864 | Shares | Sole | 2026-02-17 | |
| 2025-12-31 | $4,306,920 | 9,500 | Put | Sole | 2026-02-17 | |
| 2025-09-30 | $1,566,560 | 4,000 | Call | Sole | 2025-11-14 | |
| 2025-09-30 | $5,913,764 | 15,100 | Put | Sole | 2025-11-14 | |
| 2025-09-30 | $10,335,379 | 26,390 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $3,339,000 | 7,500 | Put | Sole | 2025-08-14 | |
| 2025-06-30 | $14,498,383 | 32,566 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $4,848,200 | 10,000 | Call | Sole | 2025-05-14 | |
| 2025-03-31 | $542,998 | 1,120 | Shares | Sole | 2025-05-14 | |
| 2025-03-31 | $3,636,150 | 7,500 | Put | Sole | 2025-05-14 | |
| 2024-12-31 | $780,432 | 1,938 | Shares | Sole | 2025-02-14 | |
| 2024-12-31 | $3,020,250 | 7,500 | Put | Sole | 2025-02-14 | |
| No filing history on record for this holder in this stock. | ||||||