Nantahala Capital Management, LLC
Filing Date
Global Rank
#1,139
/ 7,976
▲ 147
Top Industry
Biotechnology
36.4%
3Y Alpha vs SPY
-2.5%
Period ended 9 months ago
Filed Nov 14, 2025 · 7mo
23 quarters · since Mar 2020
Clone Performance
Jun 2023–Jun 2026 · vs SPYHypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.
Cloned portfolio
+65.5%
SPY
+76.3%
Annualised alpha
-2.5%
Max drawdown
−28.5%
Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.
Portfolio Concentration
129 positions · as of Sep 30, 2025 · Δ vs Jun 30, 2025Top Position
6.6%
+0.0 pts
Top 5
21.5%
−2.2 pts
Top 10
35.2%
−1.9 pts
HHI
202
Diversified−17
Portfolio Trend
23 quarters · across all stocks
Sector Breakdown
As of Sep 30, 2025| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 67.1% | $1,412,916,101 |
| Consumer Cyclical | 15.8% | $333,031,991 |
| Financial Services | 4.7% | $98,923,512 |
| Consumer Defensive | 3.6% | $75,030,906 |
| Communication Services | 3.3% | $69,894,283 |
| Real Estate | 2.2% | $46,950,212 |
| Industrials | 2.1% | $44,210,107 |
| Technology | 0.9% | $19,211,493 |
| Basic Materials | 0.2% | $3,685,882 |
| Energy | 0.1% | $2,849,544 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
24 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| PTON | Peloton Interactive, Inc. | +1,929,963 | 8,197,700 | $73,779,300 | |
| DXLG | Destination XL Group, Inc. | +1,928,226 | 4,505,000 | $5,901,550 | |
| TEVA | Teva Pharmaceutical Industries Ltd | +1,500,000 | 2,500,000 | $50,500,000 | |
| TLPH | Talphera, Inc. | +1,500,000 | 3,492,519 | $3,108,341 | |
| EOLS | Evolus, Inc. | +1,428,931 | 5,726,857 | $35,162,901 | |
| FLWS | 1 800 Flowers Com Inc | +1,368,065 | 3,368,065 | $15,493,099 | |
| NSPR | InspireMD, Inc. | +1,058,467 | 3,376,484 | $8,137,326 | |
| CWH | Camping World Holdings, Inc. | +1,000,000 | 2,000,000 | $31,580,000 | |
| HLF | Herbalife Ltd. | +620,133 | 7,742,431 | $65,346,117 | |
| QNCX | Quince Therapeutics, Inc. | +545,427 | 3,073,729 | $5,010,178 | |
| BVS | Bioventus Inc. | +529,820 | 5,810,662 | $38,873,328 | |
| ZVRA | Zevra Therapeutics, Inc. | +500,000 | 1,971,936 | $18,753,111 | |
| EHTH | eHealth, Inc. | +450,000 | 1,761,441 | $7,591,810 | |
| SVRA | Savara Inc | +450,000 | 8,775,375 | $31,328,088 | |
| FULC | Fulcrum Therapeutics, Inc. | +382,485 | 4,670,784 | $42,971,212 | |
| XNCR | Xencor Inc | +279,897 | 1,100,000 | $12,903,000 | |
| CMCO | Columbus Mckinnon Corp | +246,372 | 450,000 | $6,453,000 | |
| AVTX | Avalo Therapeutics, Inc. | +240,000 | 1,235,000 | $15,696,850 | |
| AVR | Anteris Technologies Global Corp. | +225,000 | 1,918,666 | $8,633,997 | |
| GPCR | Structure Therapeutics Inc. | +200,000 | 518,553 | $14,519,484 | |
| ESTA | Establishment Labs Holdings Inc. | +197,962 | 1,973,492 | $80,893,437 | |
| ABEO | Abeona Therapeutics Inc. | +195,000 | 5,084,665 | $26,847,031 | |
| TLSI | TriSalus Life Sciences, Inc. | +40,245 | 2,040,245 | $9,487,139 | |
| DSGR | Distribution Solutions Group, Inc. | +19,539 | 230,339 | $6,928,597 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CMPS | COMPASS Pathways plc | −2,450,000 | 1,729,930 | $9,912,498 | |
| AMLX | Amylyx Pharmaceuticals, Inc. | −1,998,721 | 935,684 | $12,715,945 | |
| VSTM | Verastem, Inc. | −1,661,832 | 1,292,903 | $11,416,333 | |
| TNGX | Tango Therapeutics, Inc. | −1,629,646 | 1,809,948 | $15,203,563 | |
| ILPT | Industrial Logistics Properties Trust | −1,530,946 | 1,675,273 | $9,766,841 | |
| FOSL | Fossil Group, Inc. | −1,346,646 | 3,741,157 | $9,614,773 | |
| QURE | uniQure N.V. | −1,044,360 | 1,007,492 | $58,807,308 | |
| SVC | Service Properties Trust | −1,000,000 | 7,057,887 | $19,126,873 | |
| ABVX | Abivax S.A. | −925,430 | 557,564 | $47,337,183 | |
| RSVR | Reservoir Media, Inc. | −491,176 | 950,960 | $7,740,814 | |
| KROS | Keros Therapeutics, Inc. | −387,503 | 1,483,189 | $23,464,049 | |
| HGV | Hilton Grand Vacations Inc. | −321,105 | 2,242,753 | $93,769,502 | |
| KOD | Kodiak Sciences Inc. | −300,000 | 290,884 | $4,761,771 | |
| NKTR | Nektar Therapeutics | −291,239 | 418,522 | $23,813,901 | |
| CNTX | Context Therapeutics Inc. | −273,534 | 1,661,950 | $1,610,429 | |
| ACHV | Achieve Life Sciences, Inc. | −250,000 | 648,885 | $2,043,987 | |
| MLYS | Mineralys Therapeutics, Inc. | −195,269 | 158,713 | $6,018,396 | |
| CNTA | Centessa Pharmaceuticals plc | −150,000 | 404,803 | $9,816,472 | |
| COGT | Cogent Biosciences, Inc. | −148,700 | 1,506,989 | $21,640,362 | |
| AMRX | Amneal Pharmaceuticals, Inc. | −142,874 | 4,224,564 | $42,287,885 | |
| IMAX | Imax Corp | −137,843 | 996,150 | $32,623,912 | |
| TBBK | Bancorp, Inc. | −116,169 | 852,334 | $63,831,293 | |
| ALTG | Alta Equipment Group Inc. | −107,995 | 934,774 | $6,767,763 | |
| KPRX | Kiora Pharmaceuticals Inc | −54,683 | 156,427 | $434,867 | |
| DYN | Dyne Therapeutics, Inc. | −42,178 | 702,884 | $8,891,482 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
21 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| EW | Edwards Lifesciences Corp | 1,800,000 | $139,986,000 | |
| REGN | Regeneron Pharmaceuticals, Inc. | 40,000 | $22,490,800 | |
| GUTS | Fractyl Health, Inc. | 12,136,917 | $19,297,698 | |
| DNTH | Dianthus Therapeutics, Inc. /DE/ | 375,000 | $14,756,250 | |
| HOOD | Robinhood Markets, Inc. | 100,000 | $14,318,000 | |
| ALGN | Align Technology Inc | 100,000 | $12,522,000 | |
| GERN | Geron Corp | 9,025,000 | $12,364,250 | |
| LBRX | Lb Pharmaceuticals Inc | 675,000 | $10,658,250 | |
| MDXG | Mimedx Group, Inc. | 1,466,566 | $10,236,630 | |
| DRIO | DarioHealth Corp. | 563,233 | $9,772,092 | |
| CYTK | Cytokinetics Inc | 150,000 | $8,244,000 | |
| XFOR | X4 Pharmaceuticals, Inc | 2,228,350 | $7,620,957 | |
| DCTH | Delcath Systems, Inc. | 666,435 | $7,164,176 | |
| CGON | CG Oncology, Inc. | 109,449 | $4,408,605 | |
| BRCC | BRC Inc. | 2,630,517 | $4,103,606 | |
| AGIO | Agios Pharmaceuticals, Inc. | 100,000 | $4,014,000 | |
| RYAM | Rayonier Advanced Materials Inc. | 510,510 | $3,685,882 | |
| AQST | Aquestive Therapeutics, Inc. | 600,000 | $3,354,000 | |
| MAZE | Maze Therapeutics, Inc. | 93,351 | $2,420,591 | |
| KIDS | Orthopediatrics Corp | 49,449 | $916,289 | |
| ANIK | Anika Therapeutics, Inc. | 20,961 | $197,033 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
13 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| GOGO | Gogo Inc. | 1,044,415 | $15,332,012 | |
| URGN | UroGen Pharma Ltd. | 1,006,703 | $13,791,831 | |
| RZLT | Rezolute, Inc. | 2,291,395 | $10,219,621 | |
| DKS | Dick's Sporting Goods, Inc. | 40,000 | $7,912,400 | |
| SNDX | Syndax Pharmaceuticals Inc | 754,503 | $7,065,920 | |
| EYPT | EyePoint, Inc. | 593,091 | $5,580,986 | |
| OLPX | Olaplex Holdings, Inc. | 650,000 | $910,000 | |
| FBIO | Fortress Biotech, Inc. | 325,520 | $605,467 | |
| XGN | Exagen Inc. | 61,186 | $427,078 | |
| LADR | Ladder Capital Corp | 25,401 | $273,060 | |
| PLCE | Childrens Place, Inc. | 57,030 | $252,642 | |
| OKUR | OnKure Therapeutics, Inc. | 54,208 | $129,557 | |
| TACT | Transact Technologies Inc | 15,046 | $55,068 | |
| No positions match the current search. | ||||
1 positions ·
$2,849,544 total
· Energy only
· as of Sep 30, 2025
All sectors
Basic Materials
Communication Services
Consumer Cyclical
Consumer Defensive
Energy
Financial Services
Healthcare
Industrials
Real Estate
Technology
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| KOS |
Kosmos Energy Ltd.
Energy
|
Held | 1,716,593 | $2,849,544 | 100.00% |