Pivotal bioVenture Partners Investment Advisor LLC

Venture Capital

CIK

1844645

Location

SAN FRANCISCO, CA

Portfolio Value

Small $279,605,926

Diversification

Moderately concentrated

Filing Date

Global Rank

#3,214 / 8,232 ▲ 376

Top Industry

Biotechnology 95.9%

3Y Alpha vs SPY

-7.0%

Period ended 2 months ago

Filed May 14, 2026 · 31d

22 quarters · since Dec 2020

Clone Performance

Jun 2023–Jun 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+51.4%

SPY

+76.3%

Annualised alpha

-6.0%

Max drawdown

−49.0%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

12 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

28.5%

+3.8 pts

Top 5

78.4%

−0.8 pts

Top 10

98.4%

−1.6 pts

HHI

1,585

Moderately concentrated+77

Portfolio Trend

22 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$279,605,926	12

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

1 positions

Ticker	Company	Δ Shares	Shares	Value	Open
TRVI	Trevi Therapeutics, Inc.	+296,944	1,553,726	$18,535,951
No positions match the current search.

Trimmed

Positions the filer reduced

2 positions

Ticker	Company	Δ Shares	Shares	Value
OCS	Oculis Holding AG	−608,375	1,680,283	$44,678,724
ARQT	Arcutis Biotherapeutics, Inc.	−10,732	1,355,892	$31,944,815
No positions match the current search.

New Positions

Positions the filer opened this quarter

2 positions

Ticker	Company	Shares	Value
AVTX	Avalo Therapeutics, Inc.	295,933	$4,418,279
RLYB	Rallybio Corp	300,579	$2,696,193
No positions match the current search.

Sold Out

Positions the filer fully exited

No qualifying positions this quarter.

Portfolio Positions

Compact Export CSV View 13F filing

12 positions · $279,605,926 total · as of Mar 31, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
PCVX	Vaxcyte, Inc. Healthcare	Held	1,372,425	0	$79,751,616	+25.9%	28.52%
OCS	Oculis Holding AG Healthcare	Reduced	1,680,283	-608,375	$44,678,724	−2.2%	15.98%
EVMN	Evommune, Inc. Healthcare	Held	1,926,943	0	$44,300,419	+34.3%	15.84%
ARQT	Arcutis Biotherapeutics, Inc. Healthcare	Reduced	1,355,892	-10,732	$31,944,815	−19.5%	11.42%
TRVI	Trevi Therapeutics, Inc. Healthcare	Added	1,553,726	+296,944	$18,535,951	+17.8%	6.63%
IMNM	Immunome Inc. Healthcare	Held	732,512	0	$16,020,037	+1.8%	5.73%
MPLT	MapLight Therapeutics, Inc. Healthcare	Held	611,447	0	$12,430,717	+15.7%	4.45%
ZBIO	Zenas BioPharma, Inc. Healthcare	Held	591,991	0	$11,573,424	−46.2%	4.14%
BIOA	BioAge Labs, Inc. Healthcare	Held	653,374	0	$11,427,511	+32.2%	4.09%
AVTX	Avalo Therapeutics, Inc. Healthcare	NEW	295,933	NEW	$4,418,279	NEW	1.58%
RLYB	Rallybio Corp Healthcare	NEW	300,579	NEW	$2,696,193	NEW	0.96%
RXRX	Recursion Pharmaceuticals, Inc. Healthcare	Held	595,518	0	$1,828,240	−24.9%	0.65%