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Equibles

TWO SIGMA INVESTMENTS, LP

Position in AYTU — Aytu Biopharma, Inc

CIK 1179392 NEW YORK, NY
Back to AYTU Full portfolio

Position in AYTU

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$226,450
-$106,536 QoQ
Shares Held
105,326
-13.6% QoQ
Ownership
0.981%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#7
of 38 holders
Holding Since
Jun 2020
9 quarters on record
Voting authority Sole 99% Shared 0% None 1%

Common Shares in AYTU Over Time

Shares Held

Position Value (USD)

Position in Drug Manufacturers - Specialty & Generic

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $775,744,366 across 48 Drug Manufacturers - Specialty & Generic names. AYTU ranks #40 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 NBIX
Neurocrine Biosciences Inc
 2,076,260 $349,932,860
2 BCRX
Biocryst Pharmaceuticals Inc
 6,775,349 $67,753,490
3 SUPN
Supernus Pharmaceuticals, Inc.
 1,184,378 $55,085,420
4 ALKS
Alkermes plc.
 1,038,311 $54,407,496
5 KNSA
Kiniksa Pharmaceuticals International, plc
 561,480 $35,906,646
6 ZTS
Zoetis Inc.
 386,428 $27,768,716
7 LQDA
Liquidia Corp
 266,829 $21,274,276
8 IRWD
Ironwood Pharmaceuticals Inc
 4,556,089 $19,181,134

All Filings in AYTU

Export CSV
9 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $226,450 105,326
2026-03-31 $332,986 121,973
2025-12-31 $278,545 107,133
2025-09-30 $129,223 68,736
2025-06-30 $76,376 35,035
2022-12-31 $2,834 14,917
2022-09-30 $5,016 26,403
2022-06-30 $28,200 40,871
2020-06-30 $138,303 97,397