Position in BBIO
as of Dec 31, 2025
· filed Feb 17, 2026
Position Value
$107,165,167
+$20,801,673 QoQ
Shares Held
1,401,035
-15.7% QoQ
Ownership
0.715%
of shares outstanding
% of Portfolio
0.21%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2020
20 quarters on record
Voting authority
Sole 96%
Shared 0%
None 4%
Common Shares in BBIO Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Dec 31, 2025TWO SIGMA ADVISERS, LP holds $2,539,427,813 across 228 Biotechnology names. BBIO ranks #6 (4.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | REGN |
Regeneron Pharmaceuticals, Inc.
|
604,540 | $466,626,289 | |
| 2 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,132,560 | $450,362,484 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
3,052,111 | $241,452,501 | |
| 4 | MRNA |
Moderna, Inc.
|
7,729,700 | $227,948,853 | |
| 5 | ARGX |
Argenx SE
|
135,500 | $113,948,725 | |
| 6 | BBIO |
BridgeBio Pharma, Inc.
This page
|
1,401,035 | $107,165,167 | |
| 7 | VKTX |
Viking Therapeutics, Inc.
|
2,129,228 | $74,906,241 | |
| 8 | INSM |
INSMED Inc
|
395,000 | $68,745,800 |
All Filings in BBIO
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20 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2025-12-31 | $107,165,167 | 1,401,035 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $86,363,494 | 1,662,755 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $72,717,494 | 1,684,055 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $9,442,968 | 273,155 | Shares | Sole | 2025-05-15 | |
| 2024-09-30 | $1,040,168 | 40,855 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $6,403,930 | 252,820 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $9,333,356 | 301,855 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $14,604,049 | 361,755 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $9,969,310 | 378,055 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $6,798,214 | 395,245 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $5,291,258 | 319,135 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $1,839,734 | 241,435 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $2,452,198 | 246,700 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $374,822 | 41,280 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $278,922 | 27,480 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $899,635 | 53,935 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $6,995,347 | 149,250 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $15,681,960 | 257,250 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $27,501,320 | 446,450 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $8,952,749 | 125,900 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||