TWO SIGMA SECURITIES, LLC

Broker-Dealer

Position in INO — Inovio Pharmaceuticals, Inc.

CIK 1450144 NEW YORK, NY

Position in INO

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$17,553

-$29,373 QoQ

Shares Held

15,958

-30.6% QoQ

Ownership

0.015%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#41

of 101 holders

Holding Since

Mar 2021

9 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

TWO SIGMA SECURITIES, LLC holds $22,805,438 across 104 Biotechnology names. INO ranks #78 (0.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	REGN	Regeneron Pharmaceuticals, Inc.	5,761	$3,592,213
2	ALNY	Alnylam Pharmaceuticals, Inc.	5,585	$1,681,252
3	BBIO	BridgeBio Pharma, Inc.	17,689	$1,317,476
4	MDGL	Madrigal Pharmaceuticals, Inc.	2,219	$1,191,492
5	INSM	INSMED Inc	10,338	$1,102,237
6	HALO	Halozyme Therapeutics, Inc.	12,525	$980,331
7	ARWR	Arrowhead Pharmaceuticals, Inc.	11,256	$917,476
8	AXSM	Axsome Therapeutics, Inc.	3,708	$907,607

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$17,553	15,958	-30.6%	Shares	Sole	2026-08-14
2025-06-30	$46,926	23,003	-78.8%	Shares	Sole	2025-08-14
2023-12-31	$55,312	108,455	+20.0%	Shares	Sole	2024-02-14
2023-09-30	$35,262	90,416	-20.1%	Shares	Sole	2023-11-14
2023-06-30	$50,934	113,188	+401.8%	Shares	Sole	2023-08-14
2022-12-31	$35,188	22,557	-54.9%	Shares	Sole	2023-02-14
2022-06-30	$86,603	50,060	+87.1%	Shares	Sole	2022-08-15
2022-03-31	$96,054	26,756	+55.8%	Shares	Sole	2022-05-16
2021-03-31	$159,337	17,170	—	Shares	Sole	2021-05-17
No filing history on record for this holder in this stock.