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Equibles

JANE STREET GROUP, LLC

Position in KPTI — Karyopharm Therapeutics Inc.

CIK 1595888 NEW YORK, NY
Back to KPTI Full portfolio

Position in KPTI

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$324,100
-$265,768 QoQ
Shares Held
33,173
-68.7% QoQ
Ownership
0.146%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#55
of 96 holders
Holding Since
Mar 2020
23 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in KPTI Over Time

Shares Held

Position Value (USD)

Derivatives in KPTI

reported options exposure · as of Jun 30, 2026
CallValue
$286,261
CallShares
29,300
PutValue
$232,526
PutShares
23,800

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,372,861,470 across 292 Biotechnology names. KPTI ranks #145 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 BBIO
BridgeBio Pharma, Inc.
 2,934,193 $218,538,693
2 MDGL
Madrigal Pharmaceuticals, Inc.
 191,541 $102,847,939
3 AXSM
Axsome Therapeutics, Inc.
 403,995 $98,885,855
4 TGTX
Tg Therapeutics, Inc.
 1,752,646 $96,290,370
5 EXEL
Exelixis, Inc.
 1,402,438 $76,306,651
6 QURE
uniQure N.V.
 1,610,483 $74,178,846
7 HALO
Halozyme Therapeutics, Inc.
 694,684 $54,372,915
8 TVTX
Travere Therapeutics, Inc.
 938,699 $53,327,489

All Filings in KPTI

Export CSV
44 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $286,261 29,300
2026-06-30 $232,526 23,800
2026-06-30 $324,100 33,173
2026-03-31 $589,868 105,901
2026-03-31 $80,208 14,400
2026-03-31 $2,636,838 473,400
2025-12-31 $261,522 35,533
2025-12-31 $147,936 20,100
2025-12-31 $262,752 35,700
2025-09-30 $84,366 12,900
2025-03-31 $42,710 11,420
2024-12-31 $505,854 748,306
2024-09-30 $169,942 204,750
2024-06-30 $1,345,378 1,549,976
2024-03-31 $259,190 171,650
2023-12-31 $238,272 275,460
2023-06-30 $1,185,629 662,363
2022-12-31 $330,941 97,336
2022-09-30 $80,633 14,768
2022-06-30 $940,772 208,597
2022-03-31 $1,398,089 189,700
2022-03-31 $3,072,132 416,843
2022-03-31 $699,413 94,900
2021-12-31 $130,529 20,300
2021-12-31 $1,331,929 207,143
2021-12-31 $853,261 132,700
2021-09-30 $164,868 28,328
2021-09-30 $130,368 22,400
2021-09-30 $131,532 22,600
2021-06-30 $220,848 21,400
2021-06-30 $162,024 15,700
2021-06-30 $278,040 26,942
2021-03-31 $461,828 43,900
2021-03-31 $771,378 73,325
2020-12-31 $1,113,012 71,900
2020-12-31 $828,180 53,500
2020-12-31 $1,098,429 70,958
2020-09-30 $500,780 34,300
2020-09-30 $1,203,404 82,425
2020-09-30 $315,360 21,600
2020-06-30 $2,477,352 130,800
2020-06-30 $943,212 49,800
2020-06-30 $2,036,409 107,519
2020-03-31 $2,577,982 134,200