SILVERARC CAPITAL MANAGEMENT, LLC

Position in KPTI — Karyopharm Therapeutics Inc.

CIK 1816307 BOSTON, MA

Position in KPTI

as of Jun 30, 2026 · filed Aug 13, 2026 Compact

Position Value

$2,906,184

+$2,503,295 QoQ

Shares Held

297,460

+648.6% QoQ

Ownership

1.31%

of shares outstanding

% of Portfolio

0.32%

of 13F equity value

Holder Rank

#24

of 96 holders

Holding Since

Mar 2023

9 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

SILVERARC CAPITAL MANAGEMENT, LLC holds $802,586,993 across 53 Biotechnology names. KPTI ranks #43 (0.4% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ASND	Ascendis Pharma A/S	206,234	$55,006,732
2	CELC	Celcuity Inc.	500,996	$52,414,201
3	COGT	Cogent Biosciences, Inc.	1,280,707	$49,563,360
4	URGN	UroGen Pharma Ltd.	1,301,979	$47,912,827
5	IMNM	Immunome Inc.	2,017,009	$42,740,420
6	DNTH	Dianthus Therapeutics, Inc. /DE/	390,000	$38,017,200
7	RYTM	Rhythm Pharmaceuticals, Inc.	311,461	$34,581,514
8	ORKA	Oruka Therapeutics, Inc.	352,802	$33,576,166

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$2,906,184	297,460	-50.1%	Shares	Sole	2026-08-13
2024-12-31	$402,889	595,990	+6.7%	Shares	Sole	2025-02-14
2024-09-30	$463,526	558,466	0.0%	Shares	Sole	2024-11-14
2024-06-30	$484,748	558,466	0.0%	Shares	Sole	2024-08-14
2024-03-31	$843,283	558,466	-0.6%	Shares	Sole	2024-05-15
2023-12-31	$486,091	561,955	0.0%	Shares	Sole	2024-02-14
2023-09-30	$753,019	561,955	+8.3%	Shares	Sole	2023-11-13
2023-06-30	$928,983	518,985	-66.3%	Shares	Sole	2023-08-14
2023-03-31	$5,996,147	1,541,426	—	Shares	Sole	2023-05-15
No filing history on record for this holder in this stock.