SILVERARC CAPITAL MANAGEMENT, LLC
Filing Date
Global Rank
#1,952
/ 8,622
▲ 296
· as of Mar 2026
Top Industry
Biotechnology
92.4%
3Y Alpha vs SPY
-8.1%
Period ended 4 months ago
Filed May 14, 2026 · 3mo
22 quarters · since Dec 2020
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+57.8%
SPY
+67.9%
Annualised alpha
-2.4%
Max drawdown
−50.3%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 99% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
66 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
6.8%
−1.4 pts
Top 5
28.8%
−2.8 pts
Top 10
49.0%
−2.8 pts
HHI
340
Diversified−17
Portfolio Trend
22 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 98.6% | $836,361,322 |
| Financial Services | 1.4% | $12,283,297 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
16 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| GLUE | Monte Rosa Therapeutics, Inc. | +972,974 | 2,002,040 | $32,933,558 | |
| IMNM | Immunome Inc. | +724,068 | 1,850,278 | $40,465,579 | |
| ERAS | Erasca, Inc. | +534,228 | 1,851,812 | $29,962,318 | |
| KALV | KalVista Pharmaceuticals, Inc. | +449,289 | 2,876,407 | $57,902,072 | |
| CERS | Cerus Corp | +362,164 | 3,176,547 | $5,781,315 | |
| SNDX | Syndax Pharmaceuticals Inc | +246,088 | 888,987 | $20,766,736 | |
| RYTM | Rhythm Pharmaceuticals, Inc. | +170,050 | 306,000 | $26,612,820 | |
| IBIO | iBio, Inc. | +120,000 | 226,000 | $429,400 | |
| ASND | Ascendis Pharma A/S | +75,430 | 124,658 | $28,513,024 | |
| COGT | Cogent Biosciences, Inc. | +68,935 | 1,314,189 | $50,583,134 | |
| NUVL | Nuvalent, Inc. | +43,484 | 354,914 | $36,360,939 | |
| FULC | Fulcrum Therapeutics, Inc. | +25,299 | 419,949 | $3,221,008 | |
| ABEO | Abeona Therapeutics Inc. | +21,204 | 648,942 | $2,907,260 | |
| CNTA | Centessa Pharmaceuticals plc | +8,142 | 466,345 | $18,523,223 | |
| GH | Guardant Health, Inc. | +6,600 | 98,514 | $9,099,738 | |
| EWTX | Edgewise Therapeutics, Inc. | +563 | 42,615 | $1,342,372 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| GUTS | Fractyl Health, Inc. | −8,138,416 | 1,701,625 | $779,344 | |
| TELA | TELA Bio, Inc. | −388,200 | 2,259,312 | $1,400,773 | |
| AARD | Aardvark Therapeutics, Inc. | −270,255 | 33,684 | $126,988 | |
| ADGM | Adagio Medical Holdings, Inc. | −263,412 | 251,972 | $289,767 | |
| ELUT | Elutia Inc. | −253,294 | 2,498,020 | $2,622,921 | |
| URGN | UroGen Pharma Ltd. | −235,776 | 1,503,045 | $27,024,749 | |
| CGON | CG Oncology, Inc. | −194,809 | 166,349 | $11,258,500 | |
| CMPX | Compass Therapeutics, Inc. | −192,294 | 859,049 | $4,544,369 | |
| VCYT | Veracyte, Inc. | −177,858 | 179,700 | $5,788,137 | |
| CGEN | Compugen Ltd | −163,960 | 3,315,845 | $7,062,749 | |
| ABVX | Abivax S.A. | −119,663 | 302,530 | $33,686,715 | |
| DNTH | Dianthus Therapeutics, Inc. /DE/ | −95,390 | 654,746 | $54,946,284 | |
| CCCC | C4 Therapeutics, Inc. | −82,439 | 1,911,785 | $5,027,994 | |
| INSM | INSMED Inc | −35,406 | 35,850 | $5,862,192 | |
| KOD | Kodiak Sciences Inc. | −31,192 | 991,930 | $37,812,371 | |
| TRVI | Trevi Therapeutics, Inc. | −30,113 | 511,127 | $6,097,745 | |
| BIIB | Biogen Inc. | −24,445 | 50,967 | $9,343,780 | |
| CELC | Celcuity Inc. | −17,229 | 357,903 | $40,851,048 | |
| ORIC | Oric Pharmaceuticals, Inc. | −16,594 | 1,100,010 | $13,937,126 | |
| BNTC | Benitec Biopharma Inc. | −13,992 | 717,725 | $7,643,771 | |
| SRZN | Surrozen, Inc./DE | −13,068 | 144,255 | $4,202,148 | |
| CLDX | Celldex Therapeutics, Inc. | −12,696 | 178,378 | $5,658,150 | |
| PRAX | Praxis Precision Medicines, Inc. | −10,913 | 71,552 | $23,053,338 | |
| CTNM | Contineum Therapeutics, Inc. | −5,811 | 301,729 | $3,940,580 | |
| PCVX | Vaxcyte, Inc. | −3,806 | 144,981 | $8,424,845 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
21 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ZBIO | Zenas BioPharma, Inc. | 1,135,935 | $22,207,529 | |
| SRRK | Scholar Rock Holding Corp | 339,613 | $16,695,375 | |
| ALKS | Alkermes plc. | 460,314 | $16,276,703 | |
| IRON | Disc Medicine, Inc. | 196,028 | $12,534,030 | |
| HLXC | Helix Acquisition Corp. III | 1,208,986 | $12,283,297 | |
| XENE | Xenon Pharmaceuticals Inc. | 197,759 | $11,499,685 | |
| IMVT | Immunovant, Inc. | 414,236 | $10,289,622 | |
| SVRA | Savara Inc | 1,430,982 | $7,813,161 | |
| ORKA | Oruka Therapeutics, Inc. | 150,908 | $7,402,037 | |
| CYTK | Cytokinetics Inc | 71,203 | $4,692,989 | |
| CLYM | Climb Bio, Inc. | 684,908 | $4,691,619 | |
| ZURA | Zura Bio Ltd | 560,651 | $3,335,873 | |
| CAMP | Camp4 Therapeutics Corp | 653,594 | $2,882,349 | |
| ANNX | Annexon, Inc. | 496,461 | $2,750,393 | |
| CBIO | Crescent Biopharma, Inc. | 130,500 | $2,397,285 | |
| MNPR | Monopar Therapeutics | 43,488 | $2,382,707 | |
| OVID | Ovid Therapeutics Inc. | 1,000,000 | $2,220,000 | |
| CMPS | COMPASS Pathways plc | 300,000 | $1,659,000 | |
| NMRA | Neumora Therapeutics, Inc. | 818,156 | $1,595,404 | |
| REPL | Replimune Group, Inc. | 171,936 | $1,315,310 | |
| GENB | Generate Biomedicines, Inc. | 100,000 | $1,250,000 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
18 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| VRDN | Viridian Therapeutics, Inc.\DE | 348,569 | $10,847,467 | |
| PFE | Pfizer Inc | 419,134 | $10,436,436 | |
| AVTX | Avalo Therapeutics, Inc. | 524,436 | $9,523,757 | |
| GOSS | Gossamer Bio, Inc. | 2,135,722 | $6,620,738 | |
| LXEO | Lexeo Therapeutics, Inc. | 617,608 | $6,132,847 | |
| AMLX | Amylyx Pharmaceuticals, Inc. | 506,242 | $6,115,403 | |
| SLNO | Soleno Therapeutics Inc | 117,485 | $5,439,555 | |
| OLMA | Olema Pharmaceuticals, Inc. | 206,280 | $5,157,000 | |
| MLYS | Mineralys Therapeutics, Inc. | 94,983 | $3,446,933 | |
| RLAY | Relay Therapeutics, Inc. | 398,167 | $3,368,492 | |
| QURE | uniQure N.V. | 126,047 | $3,016,304 | |
| TARS | Tarsus Pharmaceuticals, Inc. | 36,124 | $2,957,833 | |
| KYMR | Kymera Therapeutics, Inc. | 34,589 | $2,691,370 | |
| CTMX | CytomX Therapeutics, Inc. | 385,974 | $1,644,249 | |
| XFOR | X4 Pharmaceuticals, Inc | 357,387 | $1,429,548 | |
| FDMT | 4D Molecular Therapeutics, Inc. | 100,000 | $750,000 | |
| RAPP | Rapport Therapeutics, Inc. | 9,659 | $293,054 | |
| PALI | Palisade Bio, Inc. | 102,108 | $239,953 | |
| No positions match the current search. | ||||
66 tracked positions ·
$848,644,619 total
· filing declares
73 positions · $979,812,415
· as of Mar 31, 2026
Showing 1–50
of 66 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| KALV |
KalVista Pharmaceuticals, Inc.
Healthcare
|
Added | 2,876,407 | $57,902,072 | 6.82% | |
| DNTH |
Dianthus Therapeutics, Inc. /DE/
Healthcare
|
Reduced | 654,746 | $54,946,284 | 6.47% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
Added | 1,314,189 | $50,583,134 | 5.96% | |
| CELC |
Celcuity Inc.
Healthcare
|
Reduced | 357,903 | $40,851,048 | 4.81% | |
| IMNM |
Immunome Inc.
Healthcare
|
Added | 1,850,278 | $40,465,579 | 4.77% | |
| KOD |
Kodiak Sciences Inc.
Healthcare
|
Reduced | 991,930 | $37,812,371 | 4.46% | |
| NUVL |
Nuvalent, Inc.
Healthcare
|
Added | 354,914 | $36,360,939 | 4.28% | |
| ABVX |
Abivax S.A.
Healthcare
|
Reduced | 302,530 | $33,686,715 | 3.97% | |
| GLUE |
Monte Rosa Therapeutics, Inc.
Healthcare
|
Added | 2,002,040 | $32,933,558 | 3.88% | |
| ERAS |
Erasca, Inc.
Healthcare
|
Added | 1,851,812 | $29,962,318 | 3.53% | |
| ASND |
Ascendis Pharma A/S
Healthcare
|
Added | 124,658 | $28,513,024 | 3.36% | |
| URGN |
UroGen Pharma Ltd.
Healthcare
|
Reduced | 1,503,045 | $27,024,749 | 3.18% | |
| RYTM |
Rhythm Pharmaceuticals, Inc.
Healthcare
|
Added | 306,000 | $26,612,820 | 3.14% | |
| PRAX |
Praxis Precision Medicines, Inc.
Healthcare
|
Reduced | 71,552 | $23,053,338 | 2.72% | |
| ZBIO |
Zenas BioPharma, Inc.
Healthcare
|
NEW | 1,135,935 | $22,207,529 | 2.62% | |
| SNDX |
Syndax Pharmaceuticals Inc
Healthcare
|
Added | 888,987 | $20,766,736 | 2.45% | |
| CNTA |
Centessa Pharmaceuticals plc
Healthcare
|
Added | 466,345 | $18,523,223 | 2.18% | |
| SRRK |
Scholar Rock Holding Corp
Healthcare
|
NEW | 339,613 | $16,695,375 | 1.97% | |
| ALKS |
Alkermes plc.
Healthcare
|
NEW | 460,314 | $16,276,703 | 1.92% | |
| ORIC |
Oric Pharmaceuticals, Inc.
Healthcare
|
Reduced | 1,100,010 | $13,937,126 | 1.64% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
NEW | 196,028 | $12,534,030 | 1.48% | |
| HLXC |
Helix Acquisition Corp. III
Financial Services
|
NEW | 1,208,986 | $12,283,297 | 1.45% | |
| XENE |
Xenon Pharmaceuticals Inc.
Healthcare
|
NEW | 197,759 | $11,499,685 | 1.36% | |
| CGON |
CG Oncology, Inc.
Healthcare
|
Reduced | 166,349 | $11,258,500 | 1.33% | |
| IMVT |
Immunovant, Inc.
Healthcare
|
NEW | 414,236 | $10,289,622 | 1.21% | |
| SYRE |
Spyre Therapeutics, Inc.
Healthcare
|
Reduced | 186,618 | $9,413,011 | 1.11% | |
| BIIB |
Biogen Inc.
Healthcare
|
Reduced | 50,967 | $9,343,780 | 1.10% | |
| GH |
Guardant Health, Inc.
Healthcare
|
Added | 98,514 | $9,099,738 | 1.07% | |
| PCVX |
Vaxcyte, Inc.
Healthcare
|
Reduced | 144,981 | $8,424,845 | 0.99% | |
| SVRA |
Savara Inc
Healthcare
|
NEW | 1,430,982 | $7,813,161 | 0.92% | |
| BNTC |
Benitec Biopharma Inc.
Healthcare
|
Reduced | 717,725 | $7,643,771 | 0.90% | |
| ORKA |
Oruka Therapeutics, Inc.
Healthcare
|
NEW | 150,908 | $7,402,037 | 0.87% | |
| CGEN |
Compugen Ltd
Healthcare
|
Reduced | 3,315,845 | $7,062,749 | 0.83% | |
| TRVI |
Trevi Therapeutics, Inc.
Healthcare
|
Reduced | 511,127 | $6,097,745 | 0.72% | |
| INSM |
INSMED Inc
Healthcare
|
Reduced | 35,850 | $5,862,192 | 0.69% | |
| VCYT |
Veracyte, Inc.
Healthcare
|
Reduced | 179,700 | $5,788,137 | 0.68% | |
| CERS |
Cerus Corp
Healthcare
|
Added | 3,176,547 | $5,781,315 | 0.68% | |
| CLDX |
Celldex Therapeutics, Inc.
Healthcare
|
Reduced | 178,378 | $5,658,150 | 0.67% | |
| CCCC |
C4 Therapeutics, Inc.
Healthcare
|
Reduced | 1,911,785 | $5,027,994 | 0.59% | |
| CYTK |
Cytokinetics Inc
Healthcare
|
NEW | 71,203 | $4,692,989 | 0.55% | |
| CLYM |
Climb Bio, Inc.
Healthcare
|
NEW | 684,908 | $4,691,619 | 0.55% | |
| CMPX |
Compass Therapeutics, Inc.
Healthcare
|
Reduced | 859,049 | $4,544,369 | 0.54% | |
| SRZN |
Surrozen, Inc./DE
Healthcare
|
Reduced | 144,255 | $4,202,148 | 0.50% | |
| CTNM |
Contineum Therapeutics, Inc.
Healthcare
|
Reduced | 301,729 | $3,940,580 | 0.46% | |
| ZURA |
Zura Bio Ltd
Healthcare
|
NEW | 560,651 | $3,335,873 | 0.39% | |
| FULC |
Fulcrum Therapeutics, Inc.
Healthcare
|
Added | 419,949 | $3,221,008 | 0.38% | |
| ABEO |
Abeona Therapeutics Inc.
Healthcare
|
Added | 648,942 | $2,907,260 | 0.34% | |
| CAMP |
Camp4 Therapeutics Corp
Healthcare
|
NEW | 653,594 | $2,882,349 | 0.34% | |
| ANNX |
Annexon, Inc.
Healthcare
|
NEW | 496,461 | $2,750,393 | 0.32% | |
| ELUT |
Elutia Inc.
Healthcare
|
Reduced | 2,498,020 | $2,622,921 | 0.31% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.