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SNDX · Syndax Pharmaceuticals Inc

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$12.90 -0.75 (-5.49%) At close · Oct 16
Market Cap
$1.15B
Shares
89.30M
Volume · Oct 16 2.84M Avg daily vol (3M) 1.67M

Price & Indicators

Drag to pan · scroll to zoom
20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$12.90 Open$13.65 Day$12.82–13.66 52W close$12.90–25.15 Avg vol 30d2.1M Short int18.2M · 20.4% float · 8.5d Short vol48% Last earningsAug 4, 2026 DataJan 2020–Oct 2026 Filing10-Q · Aug 4

Up next

Next earnings call
Nov 6, 2026 Est · unconfirmed · in 3 wks
filed Aug 4, 2026
call held Aug 4, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$252.00M
Trailing 12 months
Net income (TTM)
−$220.76M
Trailing 12 months
Revenue growth YoY
+91.8%
Year over year
Operating margin
-77.1%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$203.83M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+3.1%
Year over year · more shares
Price change (1Y)
-14.3%
Trailing year
Short interest
20.4%
Latest settlement · 8.5 days to cover
View all 115 metrics

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Strong Sell Momentum Very Weak Sentiment Neutral Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 20 · elevated Equity put/call 0.65
Technical
price trend
Strong Sell
50 / 200-day cross No cross
Price vs 200-day avg −37%
below
Price vs 50-day avg −30%
below
RSI (14) 20
oversold
MACD trend Negative
52-week position 0%
near low
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Weak
1-month return −27%
trailing
6-month return −39%
trailing
YTD return −39%
this year
Relative strength −45%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $18 › 200d $21 — 200d above 50d
Institutional flow Distributing
16 of 243 funds reported for Sep 30 · net -181.8K sh shares
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
20.42% of float · ▼ -11.7% MoM · 8.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
243 holders — near 3-yr high, broad support
Squeeze score 61
elevated · 0–100
Fundamentals
Strong
Revenue growth +628%
Y/Y
EPS growth +12%
Y/Y
Free cash flow $-323.2M
Quant / Vol
risk profile
Very High
Volatility 53%
annualized · 1-yr
Max drawdown −49%
past year
ATR 7.0%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the 8-K filed Aug 4, 2026
full year of 2026
Total research and development plus selling, general and adminis Non-GAAP Maintained $400M
Apr 30, 2026 $400M changed to Aug 4, 2026 $400M
2026
R&D + SG&A expense $400M

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Strong Sell
4 · 3 · 0
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−37% Bearish
Price vs 50-day avg
−30% Bearish
RSI (14)
20 Neutral
MACD trend
Negative Bearish
52-week position
0% Bearish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 2 of 6
Trend (MA cross) No cross
50d $18 › 200d $21 — 200d above 50d
Institutional flow Distributing
16 of 243 funds reported for Sep 30 · net -181.8K sh shares
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
20.42% of float · ▼ -11.7% MoM · 8.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
243 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $13 Now $13 · 0% Range high $25
vs 200-day avg -37% vs 50-day avg -30%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
Accounts activated (Tier 1+2 prescriber base) 88% 2Q26 —
Cash, cash equivalents, and short- and long-term investments $575.1M As of June 30, 2026 —
New patients on Niktimvo 300 2Q26 —
Niktimvo infusions administered 5,750 2Q26 —
Niktimvo net revenue $60.3M second quarter of 2026 —
Niktimvo net revenue (recorded by Incyte) $60.3M Second quarter 2026 —
Niktimvo net revenue to INCY $60.3M 2Q26 —
Patients treated commercially with Revuforj since launch 1,630 Since launch through 2Q26 —
Total prescriptions 1,500 second quarter of 2026 —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SNDX
Syndax Pharmaceuticals Inc
this stock
$1.15B -38.6% +627.8% — 20.4%
VRTX
Vertex Pharmaceuticals Inc / Ma
$128.95B +10.2% +46.2% 29.6 1.8%
MRNA
Moderna, Inc.
$87.04B +639.3% +4.3% — 7.7%
REGN
Regeneron Pharmaceuticals, Inc.
$81.41B +2.4% +20.8% 19.6 2.1%
CSLLY
Csl Ltd
$63.79B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Reducing
Holders
242
% held
121.5%
Reported
16 of 243
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
208
View
Short & Settlement
Short Interest Falling
Shares short
18.2M
Days to cover
8.5d
Change
-2.4M sh
View
Short Volume
Short vol %
48%
As of
Oct 16, 2026
Short Total
View
Fails to Deliver
FTD shares
466
Value
$9.1K
As of
Aug 25, 2026
View
Off-Exchange
Off-exchange %
39.3%
Week of
Sep 7, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$172.4M
Net income (FY)
$-285.4M
EPS diluted
$-3.29
View
Buybacks
Authorized
shares 7.2M
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 4, 2026
This year
12
View
Proposed Sales
Value
$752.4K
Shares
32.4K
Filed
Jul 8, 2026
View
Earnings & Events
Webcasts
Last webcast
Aug 4, 2026
View

Performance

5D 20D 120D MTD YTD
SNDX -24.1% -26.8% -38.6% -31.4% -38.6%
SPY -2.0% +0.2% +6.7% +0.1% +11.9%
vs SPY -22.1% -27.0% -45.3% -31.5% -50.5%

Capital returns

Buyback program · as of Jan 1, 2026
Authorized
shares 7.20M
Spent (derived)
—
Remaining
—

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1395937 CUSIP 87164F105 13F (30d) 17 filings 17 filers Visit website Investor relations