MANUFACTURERS LIFE INSURANCE COMPANY, THE

Insurance

Position in PBYI — Puma Biotechnology, Inc.

CIK 928047 TORONTO, A6

Position in PBYI

as of Jun 30, 2026 · filed Sep 9, 2026 Compact

Position Value

$97,774

+$22,596 QoQ

Shares Held

12,056

+2.5% QoQ

Ownership

0.023%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#95

of 160 holders

Holding Since

Mar 2020

13 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

MANUFACTURERS LIFE INSURANCE COMPANY, THE holds $1,663,805,623 across 242 Biotechnology names. PBYI ranks #210 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	554,085	$275,230,642
2	ALNY	Alnylam Pharmaceuticals, Inc.	893,795	$269,059,108
3	BBIO	BridgeBio Pharma, Inc.	1,955,733	$145,662,993
4	JAZZ	Jazz Pharmaceuticals plc	539,037	$129,891,745
5	ROIV	Roivant Sciences Ltd.	2,988,121	$105,749,602
6	REGN	Regeneron Pharmaceuticals, Inc.	147,961	$92,259,601
7	RPRX	Royalty Pharma plc	678,768	$38,058,521
8	PTCT	Ptc Therapeutics, Inc.	441,957	$36,050,432

13 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$97,774	12,056	+2.5%	Shares	Defined	2026-09-09
2026-03-31	$75,178	11,765	-12.4%	Shares	Defined	2026-05-15
2025-12-31	$79,890	13,427	-11.4%	Shares	Defined	2026-02-13
2025-09-30	$80,483	15,157	-2.7%	Shares	Defined	2025-11-14
2025-06-30	$53,425	15,576	-5.6%	Shares	Defined	2025-08-14
2025-03-31	$48,857	16,506	-7.1%	Shares	Defined	2025-05-15
2024-06-30	$57,913	17,765	-15.0%	Shares	Defined	2024-08-14
2021-06-30	$191,944	20,909	+4.9%	Shares	Defined	2021-08-12
2021-03-31	$193,709	19,929	+2.4%	Shares	Defined	2021-05-03
2020-12-31	$199,639	19,458	+2.6%	Shares	Defined	2021-02-12
2020-09-30	$191,266	18,956	0.0%	Shares	Defined	2020-11-09
2020-06-30	$197,711	18,956	-8.1%	Shares	Defined	2020-08-10
2020-03-31	$174,083	20,626	—	Shares	Defined	2020-05-15
No filing history on record for this holder in this stock.