MANUFACTURERS LIFE INSURANCE COMPANY, THE

Insurance

Position in PBYI — Puma Biotechnology, Inc.

CIK 928047 TORONTO, A6

Position in PBYI

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$75,178

-$4,712 QoQ

Shares Held

11,765

-12.4% QoQ

Ownership

0.023%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Mar 31, 2026

MANUFACTURERS LIFE INSURANCE COMPANY, THE holds $1,606,867,536 across 225 Biotechnology names. PBYI ranks #190 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	REGN	Regeneron Pharmaceuticals, Inc.	408,931	$315,956,447
2	VRTX	Vertex Pharmaceuticals Inc / Ma	553,243	$247,045,129
3	ALNY	Alnylam Pharmaceuticals, Inc.	662,365	$219,156,707
4	BBIO	BridgeBio Pharma, Inc.	1,977,080	$146,817,960
5	JAZZ	Jazz Pharmaceuticals plc	535,062	$101,153,471
6	ARGX	Argenx SE	49,330	$36,023,232
7	PTCT	Ptc Therapeutics, Inc.	425,240	$28,971,601
8	AXSM	Axsome Therapeutics, Inc.	117,093	$19,791,058

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$75,178	11,765	-12.4%	Shares	Defined	2026-05-15
2025-12-31	$79,890	13,427	-11.4%	Shares	Defined	2026-02-13
2025-09-30	$80,483	15,157	-2.7%	Shares	Defined	2025-11-14
2025-06-30	$53,425	15,576	-5.6%	Shares	Defined	2025-08-14
2025-03-31	$48,857	16,506	-7.1%	Shares	Defined	2025-05-15
2024-06-30	$57,913	17,765	-15.0%	Shares	Defined	2024-08-14
2021-06-30	$191,944	20,909	+4.9%	Shares	Defined	2021-08-12
2021-03-31	$193,709	19,929	+2.4%	Shares	Defined	2021-05-03
2020-12-31	$199,639	19,458	+2.6%	Shares	Defined	2021-02-12
2020-09-30	$191,266	18,956	0.0%	Shares	Defined	2020-11-09
2020-06-30	$197,711	18,956	-8.1%	Shares	Defined	2020-08-10
2020-03-31	$174,083	20,626	—	Shares	Defined	2020-05-15
No filing history on record for this holder in this stock.