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PBYI

Puma Biotechnology, Inc.

Company with tickers: PBYI

CIK
1401667
CUSIP
74587V107
Shares Outstanding
50,899,456
13F Activity (30d)
125 filings 120 filers
Holders: 157
Total Value: $242,640,165
Total Shares: 37,971,872
Showing 1–100 of 158 holdings by value · page 1 of 2

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 157 13F filers · Δ vs Dec 31, 2025
Top Holder
10.9%
Jun 2023 → Mar 2026 · range 10.9% – 15.2%
−0.8 pts
Top 5
35.9%
Jun 2023 → Mar 2026 · range 35.9% – 53.7%
−8.4 pts
Top 10
56.0%
Jun 2023 → Mar 2026 · range 56.0% – 79.6%
−5.2 pts
HHI
437
Jun 2023 → Mar 2026 · range 437 – 808
Broadly held −95

Quarterly Activity

vs Dec 31, 2025
New
27
Increased
63
Decreased
38
Sold Out
23
Unchanged
29
Holder count: +4
Institutional value: +15.0%
Shares held: +7.1%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega MILLENNIUM MANAGEMENT LLC +1,460,905 1,477,519
Large LSV ASSET MANAGEMENT +778,066 1,182,868
Mega UBS Group AG +406,915 534,227
Mega AMERICAN CENTURY COMPANIES INC +266,209 1,916,346
Large STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM +245,555 272,890

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large RENAISSANCE TECHNOLOGIES LLC −181,400 1,942,413
Mega TWO SIGMA INVESTMENTS, LP −149,351 13,000
Mega CITADEL ADVISORS LLC −147,511 29,959
Mega GOLDMAN SACHS GROUP INC −124,243 669,719
Small GLOBEFLEX CAPITAL L P −102,955 349,651

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 1,817,681 $11,614,981
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 1,734,649 $11,084,407
Mega VANGUARD FIDUCIARY TRUST CO 251,683 $1,608,254
Mega DEUTSCHE BANK AG\ 33,145 $211,796
Mega Vanguard Global Advisers, LLC 29,173 $186,415

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 3,797,748 $22,596,599
Large MACKENZIE FINANCIAL CORP 160,973 $957,789
Large LOS ANGELES CAPITAL MANAGEMENT LLC 148,132 $881,385
Large Qube Research & Technologies Ltd 111,520 $663,544
Large TWO SIGMA ADVISERS, LP 71,100 $423,045
Filter: New 27 Increased 63 Reduced 38 Sold out 23 Unchanged 29
Showing 100 of 158
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Small ACORN CAPITAL ADVISORS, LLC $26,399,000 10.88% 4,131,299
Mega BlackRock, Inc. $22,997,299 9.48% 3,598,952
Large ACADIAN ASSET MANAGEMENT LLC $13,046,840 5.38% 2,041,759
Large RENAISSANCE TECHNOLOGIES LLC $12,412,019 5.12% 1,942,413
Mega AMERICAN CENTURY COMPANIES INC $12,245,450 5.05% 1,916,346
Mega VANGUARD CAPITAL MANAGEMENT LLC $11,614,981 4.79% 1,817,681
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $11,084,407 4.57% 1,734,649
Mega MILLENNIUM MANAGEMENT LLC $9,441,346 3.89% 1,477,519
Mega DIMENSIONAL FUND ADVISORS LP $9,176,715 3.78% 1,436,106
Large LSV ASSET MANAGEMENT $7,558,526 3.12% 1,182,868
Large O'SHAUGHNESSY ASSET MANAGEMENT, LLC $7,272,899 3.00% 1,138,169
Mega GEODE CAPITAL MANAGEMENT, LLC $6,500,815 2.68% 1,017,342
Mega STATE STREET CORP $5,863,400 2.42% 917,590
Mid KENNEDY CAPITAL MANAGEMENT LLC $5,684,550 2.34% 889,601
Mega AQR CAPITAL MANAGEMENT LLC $5,113,237 2.11% 800,194
Large Connor, Clark & Lunn Investment Management Ltd. $5,002,079 2.06% 782,798
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $4,954,428 2.04% 775,341
Mid RITHOLTZ WEALTH MANAGEMENT $4,947,828 2.04% 774,308
Mega GOLDMAN SACHS GROUP INC $4,279,504 1.76% 669,719
Mega NORTHERN TRUST CORP Bank $4,100,799 1.69% 641,753
Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $3,438,810 1.42% 538,155
Mega UBS Group AG $3,413,710 1.41% 534,227
Large SEI INVESTMENTS CO $3,247,282 1.34% 508,182
Mega MORGAN STANLEY $2,298,748 0.95% 359,742
Mega D. E. Shaw & Co., Inc. $2,244,391 0.92% 351,235
Small GLOBEFLEX CAPITAL L P $2,234,269 0.92% 349,651
Mega Bank of New York Mellon Corp Bank $2,222,958 0.92% 347,881
Large STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM Pension $1,743,767 0.72% 272,890
Large PRUDENTIAL FINANCIAL INC $1,616,919 0.67% 253,039
Mega VANGUARD FIDUCIARY TRUST CO Bank $1,608,254 0.66% 251,683
Large Russell Investments Group, Ltd. $1,608,062 0.66% 251,653
Large FEDERATED HERMES, INC. $1,518,998 0.63% 237,715
Mega JPMORGAN CHASE & CO $1,410,425 0.58% 220,724
Mega FRANKLIN RESOURCES INC $1,376,346 0.57% 215,391
Large STATE OF WISCONSIN INVESTMENT BOARD $1,333,069 0.55% 208,618
Large Empowered Funds, LLC $1,303,821 0.54% 204,041
Large PANAGORA ASSET MANAGEMENT INC $1,245,327 0.51% 194,887
Mega FMR LLC $1,225,812 0.51% 191,833
Mid Prospera Financial Services Inc $1,105,795 0.46% 173,051
Micro Haven Private, LLC $992,111 0.41% 155,260
Small Round Rock Advisors LLC $823,747 0.34% 128,912
Mega FIRST TRUST ADVISORS LP $789,248 0.33% 123,513
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $740,696 0.31% 115,915
Mid EVERGREEN CAPITAL MANAGEMENT LLC $613,440 0.25% 96,000
Mega Invesco Ltd. $607,330 0.25% 95,044
Large STRS OHIO $584,685 0.24% 91,500
Mid OpenArc Corporate Advisory, LLC $571,847 0.24% 89,491
Mega Nuveen, LLC $505,454 0.21% 79,101
Small State of Wyoming $484,413 0.20% 75,808
Mid WINTON GROUP Ltd $423,867 0.17% 66,333
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $406,404 0.17% 63,600
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $391,419 0.16% 61,255
Small EntryPoint Capital, LLC $341,634 0.14% 53,464
Mega RHUMBLINE ADVISERS $338,900 0.14% 53,036
Small D'Orazio & Associates, Inc. $318,956 0.13% 49,915
Mega JANE STREET GROUP, LLC $303,525 0.13% 47,500
Large Man Group plc $302,726 0.12% 47,375
Mega BANK OF AMERICA CORP /DE/ Bank $257,925 0.11% 40,364
Mid Vise Technologies, Inc. $257,504 0.11% 40,298
Large Universal- Beteiligungs- und Servicegesellschaft mbH $251,178 0.10% 39,308
Small Baron Wealth Management LLC $244,596 0.10% 38,278
Mega LPL Financial LLC $233,989 0.10% 36,618
Mega DEUTSCHE BANK AG\ Bank $211,796 0.09% 33,145
Mega PRICE T ROWE ASSOCIATES INC /MD/ $200,045 0.08% 31,306
Mega CITADEL ADVISORS LLC $191,438 0.08% 29,959
Small Kathmere Capital Management, LLC $190,287 0.08% 29,779
Small VIRTUS ADVISERS, LLC $187,527 0.08% 29,347
Mega Vanguard Global Advisers, LLC $186,415 0.08% 29,173
Mid Engineers Gate Manager LP $182,754 0.08% 28,600
Mega ENVESTNET ASSET MANAGEMENT INC $169,705 0.07% 26,558
Mid Caprock Group, LLC $166,069 0.07% 25,989
Mid Metis Global Partners, LLC $161,436 0.07% 25,264
Micro C2C Wealth Management, LLC $150,931 0.06% 23,620
Large Creative Planning $147,692 0.06% 23,113
Mega CANADA PENSION PLAN INVESTMENT BOARD Pension $145,692 0.06% 22,800
Small One Wealth Advisors, LLC $134,694 0.06% 21,079
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund $131,857 0.05% 20,635
Mid PRELUDE CAPITAL MANAGEMENT, LLC $117,882 0.05% 18,448
Mid BAILARD, INC. $115,659 0.05% 18,100
Large LAZARD ASSET MANAGEMENT LLC $114,828 0.05% 17,970
Large Allspring Global Investments Holdings, LLC $109,051 0.04% 17,066
Mid Quadrature Capital Ltd $107,000 0.04% 16,745
Mega WELLS FARGO & COMPANY/MN $103,984 0.04% 16,273
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $102,808 0.04% 16,089
Large MetLife Investment Management, LLC $101,230 0.04% 15,842
Large Police & Firemen's Retirement System of New Jersey Pension $100,444 0.04% 15,719
Large CWM, LLC $97,530 0.04% 15,263
Mid XTX Topco Ltd $96,591 0.04% 15,116
Large IEQ CAPITAL, LLC $95,217 0.04% 14,901
Large Mariner, LLC $93,607 0.04% 14,649
Mega BARCLAYS PLC $89,382 0.04% 13,988
Mega ALLIANCEBERNSTEIN L.P. $88,182 0.04% 13,800
Mid Ashton Thomas Private Wealth, LLC $86,265 0.04% 13,500
Large HRT FINANCIAL LP $83,536 0.03% 13,073
Large Cerity Partners LLC $83,152 0.03% 13,013
Mega TWO SIGMA INVESTMENTS, LP $83,070 0.03% 13,000
Mid TOCQUEVILLE ASSET MANAGEMENT L.P. $82,814 0.03% 12,960
Large Cambridge Investment Research Advisors, Inc. $80,277 0.03% 12,563
Small PERKINS CAPITAL MANAGEMENT INC $79,875 0.03% 12,500
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $75,178 0.03% 11,765
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