Position in PBYI
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$83,070
-$882,918 QoQ
Shares Held
13,000
-92.0% QoQ
Ownership
0.026%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Jun 2021
19 quarters on record
Voting authority
Sole 89%
Shared 0%
None 11%
Common Shares in PBYI Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,458,107,972 across 316 Biotechnology names. PBYI ranks #276 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in PBYI
Export CSV
19 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $83,070 | 13,000 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $965,988 | 162,351 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $298,029 | 56,126 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $653,830 | 190,621 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $570,688 | 192,800 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $553,486 | 181,471 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $126,365 | 49,555 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $111,811 | 34,298 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $432,978 | 81,694 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $931,694 | 215,172 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $283,350 | 107,738 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $374,437 | 106,073 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $643,180 | 208,149 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $1,201,108 | 283,950 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $198,148 | 83,607 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $439,481 | 154,204 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $479,378 | 166,451 | Shares | Sole | 2022-05-16 | |
| 2021-09-30 | $111,599 | 15,920 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $510,022 | 55,558 | Shares | Sole | 2021-08-16 | |
| No filing history on record for this holder in this stock. | ||||||