ORBIMED ADVISORS LLC

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1055951 New York, NY

Position in RYTM

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$27,317,277

+$1,649,085 QoQ

Shares Held

314,100

+31.0% QoQ

Ownership

0.458%

of shares outstanding

% of Portfolio

0.55%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Sep 2023

11 quarters on record

Voting authority Sole 28.2712511938873.ToString("F0")% Shared 0.ToString("F0")% None 71.7287488061127.ToString("F0")%

Healthcare · as of Mar 31, 2026

ORBIMED ADVISORS LLC holds $2,871,604,021 across 72 Biotechnology names. RYTM ranks #31 (1.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	EWTX	Edgewise Therapeutics, Inc.	15,518,492	$488,832,498
2	ELVN	Enliven Therapeutics, Inc.	7,959,538	$312,013,889
3	SION	Sionna Therapeutics, Inc.	3,530,702	$141,545,843
4	MBX	MBX Biosciences, Inc.	3,637,887	$108,590,926
5	CRVS	Corvus Pharmaceuticals, Inc.	7,165,006	$104,824,037
6	ARGX	Argenx SE	136,900	$99,971,225
7	CMPX	Compass Therapeutics, Inc.	15,219,994	$80,513,768
8	GPCR	Structure Therapeutics Inc.	1,475,403	$71,114,424

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$27,317,277	314,100	+31.0%	Shares	Defined	2026-05-15
2025-12-31	$25,668,192	239,800	+11.5%	Shares	Defined	2026-02-17
2025-09-30	$21,728,200	215,152	-13.4%	Shares	Defined	2025-11-14
2025-06-30	$15,703,473	248,512	-34.6%	Shares	Defined	2025-08-14
2025-03-31	$20,128,600	380,000	-5.0%	Shares	Defined	2025-05-15
2024-12-31	$22,392,000	400,000	-8.2%	Shares	Defined	2025-02-14
2024-09-30	$22,836,801	435,900	-38.2%	Shares	Defined	2024-11-14
2024-06-30	$28,940,812	704,842	0.0%	Shares	Defined	2024-08-14
2024-03-31	$30,540,803	704,842	+31.3%	Shares	Defined	2024-05-15
2023-12-31	$24,669,432	536,642	-8.1%	Shares	Defined	2024-02-14
2023-09-30	$13,379,992	583,642	—	Shares	Defined	2023-11-14
No filing history on record for this holder in this stock.