Skip to main content
Equibles

Opaleye Management Inc.

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1595855 Boston, MA
Back to RYTM Full portfolio

Position in RYTM

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$13,601,175
+$2,903,865 QoQ
Shares Held
122,500
-0.4% QoQ
Ownership
0.178%
of shares outstanding
% of Portfolio
1.25%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2020
18 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in RYTM Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

Opaleye Management Inc. holds $678,840,611 across 50 Biotechnology names. RYTM ranks #19 (2.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 IRON
Disc Medicine, Inc.
 855,000 $62,534,700
2 URGN
UroGen Pharma Ltd.
 1,439,996 $52,991,852
3
390,000 $51,764,700
4 MGTX
MeiraGTx Holdings plc
 3,550,000 $47,960,500
5 SLGL
Sol-Gel Technologies Ltd.
 500,000 $37,070,000
6 RZLT
Rezolute, Inc.
 6,300,000 $32,760,000
7 TGTX
Tg Therapeutics, Inc.
 535,000 $29,392,900
8 IMMX
Immix Biopharma, Inc.
 2,345,000 $24,176,950

All Filings in RYTM

Export CSV
18 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $13,601,175 122,500
2026-03-31 $10,697,310 123,000
2025-12-31 $35,323,200 330,000
2025-09-30 $46,627,083 461,700
2025-06-30 $30,015,250 475,000
2025-03-31 $25,955,300 490,000
2024-12-31 $27,990,000 500,000
2024-09-30 $26,195,000 500,000
2024-06-30 $21,145,900 515,000
2024-03-31 $22,314,950 515,000
2023-12-31 $28,041,700 610,000
2023-09-30 $14,970,025 653,000
2023-06-30 $12,120,150 735,000
2023-03-31 $13,112,400 735,000
2022-12-31 $21,403,200 735,000
2022-09-30 $19,845,000 810,000
2022-06-30 $1,502,300 362,000
2020-12-31 $3,418,950 115,000