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Equibles

ROYAL BANK OF CANADA

Bank

Position in SPRB — Spruce Biosciences, Inc.

CIK 1000275 TORONTO, A6
Back to SPRB Full portfolio

Position in SPRB

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$8,964
+$5,480 QoQ
Shares Held
166
+315.0% QoQ
Ownership
0.006%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#58
of 63 holders
Holding Since
Dec 2020
16 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SPRB Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

ROYAL BANK OF CANADA holds $2,118,794,122 across 427 Biotechnology names. SPRB ranks #292 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 IONS
Ionis Pharmaceuticals Inc
 6,182,479 $490,208,754
2 VRTX
Vertex Pharmaceuticals Inc / Ma
 980,259 $486,924,048
3 ALNY
Alnylam Pharmaceuticals, Inc.
 875,859 $263,659,830
4 INCY
Incyte Corp
 1,132,050 $128,329,182
5 REGN
Regeneron Pharmaceuticals, Inc.
 174,515 $108,817,078
6 MRNA
Moderna, Inc.
 944,457 $66,140,319
7 INSM
INSMED Inc
 416,487 $44,405,840
8 HALO
Halozyme Therapeutics, Inc.
 545,761 $42,716,712

All Filings in SPRB

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16 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $8,964 166
2025-12-31 $3,484 40
2024-09-30 $1,773 3,733
2024-06-30 $111 216
2023-12-31 $26,097 8,907
2023-09-30 $21,811 9,651
2023-06-30 $5,441 2,531
2023-03-31 $207,563 93,920
2022-09-30 $127 93
2022-06-30 $295 170
2022-03-31 $1,272 633
2021-12-31 $7,920 1,776
2021-09-30 $5,444 906
2021-06-30 $6,669 595
2021-03-31 $13,230 797
2020-12-31 $8,362 344