Opaleye Management Inc.
Top Portfolio Positions
53 positions ·
$763,048,828 total
· as of Mar 31, 2026
| Ticker | Company | Shares | Value (USD) | % of Portfolio | Open |
|---|---|---|---|---|---|
| HROW |
Harrow, Inc.
Healthcare
|
2,832,230 | $99,864,429 | 13.09% | |
| LQDA |
Liquidia Corp
Healthcare
|
2,545,000 | $96,048,300 | 12.59% | |
| ETON |
Eton Pharmaceuticals, Inc.
Healthcare
|
2,860,000 | $70,584,800 | 9.25% | |
| SLGL |
Sol-Gel Technologies Ltd.
Healthcare
|
500,000 | $39,610,000 | 5.19% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
12,600,000 | $38,430,000 | 5.04% | |
| APGE |
Apogee Therapeutics, Inc.
Healthcare
|
390,000 | $32,826,300 | 4.30% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
421,000 | $26,918,740 | 3.53% | |
| URGN |
UroGen Pharma Ltd.
Healthcare
|
1,430,000 | $25,711,400 | 3.37% | |
| CBIO |
Crescent Biopharma, Inc.
Healthcare
|
1,312,615 | $24,112,737 | 3.16% | |
| STOK |
Stoke Therapeutics, Inc.
Healthcare
|
700,000 | $22,792,000 | 2.99% |
Portfolio Trend
25 quarters · across all stocks
Holdings in STOK
Shares Held
Position Value (USD)
6 quarters on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $22,792,000 | 700,000 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $22,059,300 | 695,000 | Shares | Sole | 2026-04-13 | |
| 2025-09-30 | $16,027,399 | 682,017 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $6,380,062 | 562,120 | Shares | Sole | 2025-08-15 | |
| 2025-03-31 | $1,995,000 | 300,000 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $275,750 | 25,000 | Shares | Sole | 2025-02-14 | |
| No 13F history on record for this holder in this stock. | ||||||