STOK · Stoke Therapeutics, Inc.
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AI Brief
Q2 FY26 earnings call · Aug 3, 2026TL;DR. Stoke completed enrollment of 162 patients in its Phase 3 EMPEROR study of zorevunersen in Dravet syndrome with a Q3 2027 data readout planned, and is preparing for a pre-NDA meeting with the FDA in H2 2026 ahead of an initiating rolling NDA submission in Q1 2027. The company also reported a Q2 net loss of $61.6M and ended with $420M in pro forma cash, expected to fund operations through a potential early-2028 launch.
- + Phase 3 EMPEROR enrollment of 162 patients completed with no discontinuations and a Q3 2027 data readout planned
- + Rolling NDA submission planned to initiate in Q1 2027 following a pre-NDA meeting with FDA in H2 2026
- + Pro forma cash of $420M expected to fund operations through potential U.S. launch by early 2028
- + Phase 1 OSPREY study of STK-002 in ADOA advanced with sentinel cohort dosed and initial data anticipated in H1 2027
- − Q2 net loss widened to $61.6M (vs $23.5M prior year quarter) driven by higher R&D and SG&A
- − Q2 revenue declined to $9.3M from $13.8M in the prior year quarter
- − YTD revenue fell sharply to $15.6M from $172.4M due to non-recurrence of a prior Biogen IP license performance obligation
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
Equibles Rating
blended score · not investment adviceBlended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.
Technicals
trend & momentum for long-term holders Strong SellIllustrative technical + ownership context — a signal mix, not investment advice.
Key metrics
Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.
Versus peers
Biotechnology — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
STOK
this stock
Stoke Therapeutics, Inc.
|
$1.57B | -23.5% | +404.5% | — | 17.3% |
|
VRTX
Vertex Pharmaceuticals Inc / Ma
|
$128.16B | +11.5% | +46.2% | 29.5 | 1.9% |
|
MRNA
Moderna, Inc.
|
$78.44B | +566.3% | +4.3% | — | 8.2% |
|
REGN
Regeneron Pharmaceuticals, Inc.
|
$76.40B | -3.9% | +20.8% | 18.4 | 2.5% |
|
CSLLY
Csl Ltd
|
$61.25B | — | — | — | 0.0% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every sectionPerformance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| STOK | -6.6% | -18.8% | -31.3% | -6.6% | -23.5% |
| SPY | +1.9% | +1.9% | +10.8% | +1.9% | +14.0% |
| vs SPY | -8.5% | -20.8% | -42.0% | -8.5% | -37.5% |