PRINCIPAL SECURITIES, INC.

Broker-Dealer

Position in VRTX — Vertex Pharmaceuticals Inc / Ma

CIK 12600 DES MOINES, IA

Position in VRTX

as of Jun 30, 2026 · filed Aug 4, 2026 Compact

Position Value

$2,971,438

+$34,098 QoQ

Shares Held

5,982

-9.1% QoQ

Ownership

0.002%

of shares outstanding

% of Portfolio

0.10%

of 13F equity value

Holder Rank

#585

of 1,735 holders

Holding Since

Dec 2023

11 quarters on record

Voting authority Sole 0% Shared 0% None 100%

Healthcare · as of Jun 30, 2026

PRINCIPAL SECURITIES, INC. holds $9,913,561 across 11 Biotechnology names. VRTX ranks #1 (30.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma This page	5,982	$2,971,438
2	RPRX	Royalty Pharma plc	35,574	$1,994,634
3	ARGX	Argenx SE	1,295	$1,201,462
4	INSM	INSMED Inc	6,728	$717,339
5	REGN	Regeneron Pharmaceuticals, Inc.	1,028	$640,999
6	EXEL	Exelixis, Inc.	11,237	$611,405
7	CORT	Corcept Therapeutics Inc	5,720	$497,354
8	ALNY	Alnylam Pharmaceuticals, Inc.	1,389	$418,130

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$2,971,438	5,982	-9.1%	Shares	Sole	2026-08-04
2026-03-31	$2,937,340	6,578	+4.1%	Shares	Sole	2026-05-13
2025-12-31	$2,864,781	6,319	-7.6%	Shares	Sole	2026-02-12
2025-09-30	$2,677,642	6,837	+3.6%	Shares	Sole	2025-11-12
2025-06-30	$2,938,320	6,600	+20.8%	Shares	Sole	2025-08-11
2025-03-31	$2,648,571	5,463	0.0%	Shares	Sole	2025-04-30
2024-12-31	$2,199,950	5,463	+27.1%	Shares	Sole	2025-01-30
2024-09-30	$1,999,378	4,299	+5.5%	Shares	Sole	2024-10-28
2024-06-30	$1,909,096	4,073	+38.3%	Shares	Sole	2024-07-31
2024-03-31	$1,231,457	2,946	+24.6%	Shares	Sole	2024-05-10
2023-12-31	$961,887	2,364	—	Shares	Sole	2024-05-10
No filing history on record for this holder in this stock.